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Buschke-Löwenstein Tumor (BLT): Successful Treatment of Human Papillomavirus (HPV)-Associated Squamous Cell Carcinoma With Radical Surgery and Chemotherapy.
Cureus
November 2024
Emergency Medicine, Public Health Institution Dom Zdravlja Prijedo, Prijedor, BIH.
The giant condyloma acuminatum, known as the Buschke-Löwenstein tumor (BLT), is an uncommon, slow-growing, cauliflower-like tumor located in the anogenital region. It has a high recurrence rate, is sexually transmitted, and is often linked with immunosuppression. This tumor is commonly associated with human papillomavirus (HPV) infection, making HPV one of the most prevalent sexually transmitted infections affecting the perineal and genital regions.
View Article and Find Full Text PDFCase report: A case of giant breast skin warts caused by HPV infection.
Front Oncol
August 2024
Department of Thyroid and Breast Surgery, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
GCA, also known as Buschke-Lowenstein tumor, is a rare sexually transmitted disease associated with HPV types 6 and 111. These warts are considered histologically benign, but there is a risk of localized invasion and development of malignancy. This malignant transformation occurs most often in the perianal and vulvar areas, and involvement of other sites is relatively rare2.
View Article and Find Full Text PDFClinicopathological Findings and Comprehensive Review of Buschke-Lowenstein Tumors Based on a Case Study.
J Pers Med
August 2024
Department 11, Discipline Plastic and Reconstructive Surgery, Bucharest Clinical Emergency Hospital, University of Medicine and Pharmacy Carol Davila, 050474 Bucharest, Romania.
Article Synopsis
- The Buschke-Löwenstein tumor (BLT) is a rare, exophytic tumor linked to low-risk HPV strains, primarily appearing as a large, cauliflower-like growth in genital areas, which can be locally aggressive and has a notable recurrence rate.
- A 68-year-old patient with multiple health issues presented with a sizable tumor causing erectile dysfunction and urinary problems, which was successfully surgically excised with reconstruction.
- Histopathological analysis confirmed the diagnosis, and the patient's recovery underscores the importance of early diagnosis and surgical intervention to manage BLT and prevent complications like malignancy and recurrence.
A rare presentation of a rare entity: giant condyloma (Buschke-Löwenstein) tumor.
J Surg Case Rep
July 2024
Department of Surgery, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Article Synopsis
- Giant condyloma accuminata, also known as Buschke-Lowenstein tumor, is a rare and large growth resembling a cauliflower, typically found in the anogenital area, and relates to HPV infections.
- The tumor exists on a spectrum between typical condylomas and squamous cell carcinoma, often resulting in surgical treatment due to its tendency to infiltrate soft tissue and recur.
- The case presented involves a 40-year-old male with cystic fibrosis who developed this tumor without any known HPV or common risk factors, and he was treated through near-total surgical resection.
Surgical treatment of perineal giant condylomata acuminata (Buschke Lowenstein tumor): Case series from a developing country.
Int J Surg Case Rep
August 2024
Department of Surgery, University College Hospital Ibadan, Nigeria; Department of Surgery College of Medicine University of Ibadan, University College Hospital Ibadan, Nigeria.
Article Synopsis
- Giant condylomata acuminatum (GCA), also known as Buschke-Lowenstein tumor (BLT), is a rare, slow-growing tumor linked to low-risk HPV types 6 and 11, with low chances of becoming invasive cancer.
- The study involved three patients (one woman and two men) who underwent surgical excision for their BLT, with two also receiving surgical reconstruction and achieving positive outcomes.
- The authors emphasize the need for early symptom recognition, effective treatment options, awareness of recurrence risks, and preventive strategies against HPV.
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