In France, the newly diagnosed infection rate was 372/100,000 for African immigrants versus 6/100,000 for the French-born population in 2008. In addition, people from sub-Saharan countries were at higher risk for late diagnosis than native-born French despite their more frequent use of HIV testing. The purpose of this study was to compare the mean time since the last HIV test according to migration origin. This study used data from the SIRS (a French acronym for health, inequalities, and social ruptures) cohort, which, in 2005, included 3023 households representative of the greater Paris area. HIV testing uptake and the time since the last test were studied in relation to socio-economic factors, psychosocial characteristics, and migration origin. Multivariate ANOVA analyses were performed using Stata 10. People from sub-Saharan Africa were more likely to have been tested in their lifetime (78.51%) than those of French (56.19%) or Maghreb (39.74%) origin (p<0.0000). The mean time, in years, since the last HIV test was shorter among sub-Saharan immigrants and Maghreb immigrants (2.15 and 2.53 years, respectively) than among native-born French (4.84 years) (F=12.67; p<0.0000). These differences remained significant even after adjusting for gender, age, number of steady relationships, time lived in France, and difficulty reading and/or writing French (F=5.73; p=0.0007). A gender analysis revealed the same pattern for both sexes, with greater differences in the mean duration by migration origin for women. These results and recent epidemiological data seem to show that since the early 2000s, measures aimed at increasing HIV testing and decreasing late diagnosis in sub-Saharan immigrants have been effective.
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http://dx.doi.org/10.1080/09540121.2011.554522 | DOI Listing |
Cureus
December 2024
Department of Anatomical Sciences, William Carey University College of Osteopathic Medicine, Hattiesburg, USA.
The digastric muscle is a suprahyoid muscle that is composed of an anterior belly and a posterior belly, which originate from the first and second pharyngeal arches, respectively, and they are innervated by the nerves of these arches. The digastric muscles are involved in the elevation of the hyoid bone and depression of the mandible during mastication, speech, and swallowing. In this report, we present the rare case of bilateral accessory anterior belly of the digastric muscles (ABDMs) that originated from the digastric fossa, medial to the anterior bellies.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Pharmacology Division, Council of Scientific and Industrial Research-Indian Institute of Integrative Medicine, Jammu, Jammu and Kashmir 180001, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201002, India. Electronic address:
Melanoma is an aggressive form of malignancy that originates from melanin-producing cells known as melanocytes underlying the basal layer of the epidermis with a poor prognosis, low survival rates, and limited treatment options. Although several specific and effective systematic strategies for treating melanoma have been established, the underlying molecular mechanism of melanoma progression, mortality and the promising therapeutic options remain elusive. Shikonin (SK), a natural naphthoquinone derived from a medicinal herbaceous plant, has been shown to inhibit the proliferation of several cancer cells.
View Article and Find Full Text PDFTissue Cell
January 2025
Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, Nizhny Novgorod, Russia. Electronic address:
The extracellular matrix (ECM) and its primary chemical components, including collagen, play a pivotal role in carcinogenesis and tumor progression. The ECM actively regulates cell proliferation, migration, and, importantly, resistance to various adverse factors. It is widely recognized as a key factor in modifying the resistance of tumor cells to various treatment modalities and cytotoxic compounds.
View Article and Find Full Text PDFAdv Exp Med Biol
January 2025
Institute of Biotechnology, Helsinki Institute of Life Science HiLIFE, University of Helsinki, Helsinki, Finland.
Embryonic mammary gland development unfolds with the specification of bilateral mammary lines, thereafter progressing through placode, bud, and sprout stages before branching morphogenesis. Extensive epithelial-mesenchymal interactions guide morphogenesis from embryogenesis to adulthood. Two distinct mesenchymal tissues are involved, the primary mammary mesenchyme that harbors mammary inductive capacity, and the secondary mesenchyme, the precursor of the adult stroma.
View Article and Find Full Text PDFEcon Hum Biol
January 2025
University of Perugia, Italy. Electronic address:
This paper examines internal migrant selection in Italy using individual height data from the 1951 and 1980 birth cohorts of military conscripts. Information on both place of birth and residence of conscripts allows us to compare migrants' heights to the height distributions of their non-migrant peers at the national level and to their populations of origin. Results suggest that migrants from southern Italy were negatively selected at the national level, while a positive selection in height emerged if compared to conscripts who remained in their macro-area of origin.
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