Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Creatine Supplementation in Depression: A Review of Mechanisms, Efficacy, Clinical Outcomes, and Future Directions.
Cureus
October 2024
Internal Medicine, Jagadguru Jayadeva Murugarajendra (JJM) Medical College, Davangere, IND.
Depression, affecting millions of people worldwide, is a leading cause of disability globally. It affects not only daily functioning but also interpersonal relationships and overall health by increasing the risks of chronic physical and mental illnesses. Creatine, traditionally recognized for boosting physical performance through its role in producing adenosine triphosphate, has recently shown potential as an adjunctive therapy for treating depression.
View Article and Find Full Text PDFApproaches and processes for paediatric chest X-ray classification used in the SHINE TB treatment-shortening trial.
Int J Tuberc Lung Dis
November 2024
Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Cape Town, South Africa.
Clinical and diagnostic features of central nervous system tuberculosis in Indian children - a descriptive study.
Ther Adv Infect Dis
September 2024
Columbia University Irving Medical Center, New York Presbyterian Hospital, New York, NY, USA.
Background: Children with tuberculous meningitis (TBM) present with diagnostic challenges as they often have atypical clinical features.
Objective: To describe the baseline characteristic features of children diagnosed with central nervous system (CNS) TB (TBM and tuberculoma).
Design: Retrospective descriptive study.
Cytokine and chemokine profiles in pulmonary tuberculosis with pre-diabetes.
Front Immunol
September 2024
International Center for Excellence in Research, National Institute of Allergy and Infectious Diseases (NIAID), Chennai, India.
Article Synopsis
- Tuberculosis (TB) is a major health issue in India, especially in patients with diabetes mellitus (DM), creating a serious challenge known as TB-PDM.
- The study analyzed the effects of DM on the immune response in patients with pulmonary TB by measuring various cytokine and chemokine levels in blood samples.
- Results revealed that coexisting TB and PDM lead to higher mycobacterial loads and increased cytokine and chemokine levels, suggesting that glycemic control is crucial for managing this complicated relationship between the two diseases.
The Emerging Role of Neurosteroids: Novel Drugs Brexanalone, Sepranolone, Zuranolone, and Ganaxolone in Mood and Neurological Disorders.
Cureus
July 2024
Psychiatry and Behavioral Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
Article Synopsis
- * Brexanolone and zuranolone are particularly effective for postpartum depression, providing rapid symptom relief through their action on the GABA system, as shown in clinical trials.
- * Beyond mood disorders, ganaxalone shows promise for managing epilepsy by controlling seizures via GABAergic activity, and neurosteroids may offer neuroprotection in Alzheimer's models, suggesting their potential to mitigate excitotoxicity and slow neurodegeneration.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!