Purpose: To evaluate blue-light attenuation in eyes with a tinted intraocular lens (IOL) or an untinted IOL.
Setting: Department of Ophthalmology, University Hospital of Crete, Crete, Greece.
Design: Comparative case series.
Methods: Patients had lens extraction and implantation of an Acrysof Natural tinted or Tecnis ZA9003 or Softec III untinted acrylic IOL. The luminance ratio of green (530 nm) and blue (465 nm) light (green:blue ratio) required for isoluminant perception was determined by heterochromatic flicker photometry. Patients were tested preoperatively and 20 days postoperatively. The parafoveal measure of the green:blue ratio, expressed in decibels, is proportional to the blue-light attenuation by the lens.
Results: Twenty-two patients received the tinted IOL and 21 the untinted IOL. Preoperatively, age was strongly linearly correlated with the green:blue ratio (r = 0.59, P < .001). The mean postoperative decrease in the green:blue ratio was greater in the untinted IOL group (P = .003). Postoperatively, the tinted IOL group had a significantly higher green:blue ratio than the untinted IOL group (P < .001). In the tinted IOL group, the green:blue ratio was linearly related to IOL dioptric power.
Conclusion: Less blue light reached the retina with tinted IOLs than with untinted IOLs. The absorption properties of tinted IOLs seemed to resemble those of the aging human crystalline lens, while untinted IOLs resembled the lower levels of blue-light attenuation of younger lenses. Thus, tinted IOLs may protect against the presumed blue-light hazard.
Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned.
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http://dx.doi.org/10.1016/j.jcrs.2010.12.047 | DOI Listing |
Ageing Res Rev
December 2024
Department of Health Policy and Management, College of Public Health, University of Georgia, Athens, GA 30602, USA. Electronic address:
Environ Sci Ecotechnol
July 2024
College of Agriculture and Biotechnology, Zhejiang University, Hangzhou, 310058, China.
Green-blue spaces (GBS) are pivotal in mitigating thermal discomfort. However, their management lacks guidelines rooted in epidemiological evidence for specific planning and design. Here we show how various GBS types modify the link between non-optimal temperatures and cardiovascular mortality across different thermal extremes.
View Article and Find Full Text PDFACS Chem Biol
February 2024
Laboratory of Chemical Biology, Department of Biomedical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.
Rapid and sensitive DNA detection methods that can be conducted at the point of need may aid in disease diagnosis and monitoring. However, translation of current assays has proven challenging, as they typically require specialized equipment or probe-specific modifications for every new target DNA. Here, we present minescent ultivalent ntercalating ye (LUMID), off-the-shelf bioluminescent sensors consisting of intercalating dyes conjugated to a NanoLuc luciferase, which allow for nonspecific detection of double-stranded DNA through a blue-to-green color change.
View Article and Find Full Text PDFPublic Health Res (Southampt)
October 2023
Department of Public Health, Policy and Systems, University of Liverpool, Liverpool, UK.
Background: Cross-sectional evidence suggests that living near green and blue spaces benefits mental health; longitudinal evidence is limited.
Objectives: To quantify the impact of changes in green and blue spaces on common mental health disorders, well-being and health service use.
Design: A retrospective, dynamic longitudinal panel study.
RSC Adv
October 2023
Department of Pharmacy, College of Medicine, Guangxi University Nanning 530004 China.
Hypochlorous acid is a reactive oxygen species that is widely present in the body and has been found to exhibit an elevated concentration in tumors. As a result, fluorescent probes for tumor detection have recently gained significant attention. In this study, we designed and synthesized a novel ratiometric fluorescent probe, LW-1, using coumarin as a scaffold, and characterized its spectral properties.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!