The investigations were carried out on activities of leucinearylamidase (LAP) and (GGTP) gammaglutamyltranspeptidase in serum and urine of women with physiological and prolonged pregnancy. The results shown on pathological increase of LAP-activity in serum and increase excretion of both enzymes in to the urine during prolonged pregnancy. These findings may appear very important for the explain of pathomechanism of prolonged pregnancy and diagnostic purpose.

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