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Diagnosis and treatment of calciphylaxis.

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Department of Dermatology, Burnley General Hospital, Casterton Avenue, Burnley BB10 2PQ, United Kingdom.

Calciphylaxis occurs due to calcium deposition in arterioles, which leads to ischemic ulceration of overlying skin. Two-year mortality rates from sepsis ranges from 50% to 80%. Calciphylaxis is most common in hyperparathyroidism secondary to chronic renal impairment and rarely occurs in the setting of normal renal function.

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