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http://dx.doi.org/10.4088/PCC.10l01016blu | DOI Listing |
World J Clin Cases
March 2022
Department of Pharmacy, Valenciennes Hospital, Valenciennes 59300, France.
Background: The antidepressant escitalopram is widely prescribed for the treatment of depression. It is generally well-tolerated, and cholestasis is not mentioned in its summary of product characteristics (SmPC). We present a case of cholestatic and cytolysis liver injury due to escitalopram and a VigiBase study.
View Article and Find Full Text PDFCase Rep Nephrol
September 2018
Monmouth Medical Center, Long Branch, NJ 07740, USA.
Hyponatremia is a well-known medication related side effect of selective serotonin reuptake inhibitors; despite its association with escitalopram, the newest SSRI is very rare. We did a review of literature and came across only 14 reported case of this rare association of SIADH with escitalopram. We hereby report a case of a 93-year-old female who presented with generalized tonic-clonic seizure and was diagnosed with severe hyponatremia due to escitalopram-induced syndrome of inappropriate antidiuretic hormone secretion (SIADH).
View Article and Find Full Text PDFPsychopharmacol Bull
September 2017
Drs. Sudha, Karthik, Muralidhar, Aswini, Department of Internal Medicine, Kasturba Medical College, Manipal University, Manipal, India. Drs. Navin, Dipanjan, Department of Pharmacology, Kasturba Medical College, Manipal University, Manipal, India.
Hyponatraemia is a well-established and potentially, a life-threatening adverse effect of selective serotonin receptor uptake inhibitors (SSRI). However, its occurrence secondary to syndrome of inappropriate antidiuretic hormone secretion (SIADH) with escitalopram, has been reported extremely sporadically. The reporting of such rare, but life-threatening adverse effects of escitalopram assumes immense significance in light of the fact that SSRIs presently form the mainstay of treatment of depressive disorders.
View Article and Find Full Text PDFCurr Drug Saf
March 2014
Department of Radiotherapy, B.S. Medical College, Bankura, West Bengal, India.
Although cases of Selective Serotonin Reuptake Inhibitor (SSRI) induced akathisia have often been reported in literature, this adverse effect has not adequately been mentioned in major pharmacology textbooks. As a result, SSRIinduced akathisia is very frequently under-recognized. A review of literature showed that almost all frequently used SSRIs such as Fluvoxamine, Fluoxetine, Sertraline, Citalopram have been reported to be causing akathisia.
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