A total of fifty Bulgarian Brown cows were used to test the effect of some hormonal and therapeutic preparations in combination with unspecific agents, having an irritation effect on the reticuloendothelial system, to establish their action on the quantitative and qualitative changes in the microbial flora of the uterus and the impregnantion of cows after calving. It was found that treatment after normal calving with 200,000 IU vitestrol and 20 IV hypophysin, and after rejection of the placenta with 2 g chloramphenicol, 15 g ac. citricum or sodium citrate and 0.2 g pilocarpinum hydrochloricum, coupled with the injection of 30-40 cm3 Filatov's tissue emulsion 8n the 5th day lowered the microbial count in the uterus by to 30.12% from the 1st to the 5th day and by 6.46 to 12.78% from the 10th to the 20th day. Parallel drop was established in the number of microbial species by 42%. Besides, it was noted that the cases of retentio secundinarum among the test cows and the number of cows with acute endometritis after calving decreased by 12%, on an average, the service period became shorter by 12.04 days, and the rate of conception at first insemination rose by 12% as compared with the controls.
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