AI Article Synopsis
- The study looked at how well babies develop if their moms didn't have enough iodine during pregnancy.
- They tested 86 kids when they were 12, 18, and 24 months old to see their development.
- The results showed that moms with low thyroid hormone levels early in pregnancy had babies who were more likely to have delays in development, so getting enough iodine is really important for moms during pregnancy.
Article Abstract
Objectives: To assess the psychomotor development of the progeny of women from a moderately iodine-deficient area for whom thyroid function during pregnancy was measured.
Study Design: The development of 86 children was assessed by the Bayley Scale of Infant Development at 12, 18, and 24 months.
Results: Maternal serum free thyroxine (FT(4)) levels in the first trimester of pregnancy were the major determinant of psychomotor development at 18 and 24 months. Children born from mothers with FT(4) levels <25th percentile (<10 pg/mL) had an OR of 2.1 for mild-to-severe delay. Furthermore, alterations in behavior were already observed at 12 months and were related to subsequent changes in development. Neonatal thyroid status did not influence development.
Conclusions: This study highlights the need to implement active measures of iodine supplementation periconceptionally and during pregnancy and lactation because the negative effects on development and behavior might be prevented through preemptive action.
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| http://dx.doi.org/10.1016/j.jpeds.2011.02.034 | DOI Listing |
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