In this paper, the performance of various sliding window trigonometric fast transforms for identification of protein coding regions has been analysed at the nucleotide level. It is found that, Short-Time Discrete Fourier Transform (ST-DFT) gives better identification accuracy in comparison with Short-Time Discrete Cosine Transform (ST-DCT), Short-Time Discrete Sine Transform (ST-DST) and Short-Time Discrete Hartley Transform (ST-DHT). In the proposed method, identification accuracy of protein coding regions has been improved by applying Singular Value Decomposition (SVD) on the DNA spectrum obtained using sliding window trigonometric fast transforms. The results show that, in proposed method all trigonometric fast transforms gives almost similar results in terms of area under ROC curve for GENSCAN test set.

Download full-text PDF

Source
http://dx.doi.org/10.1504/ijdmb.2011.038580DOI Listing

Publication Analysis

Top Keywords

trigonometric fast
16
fast transforms
16
short-time discrete
16
sliding window
12
window trigonometric
12
singular decomposition
8
protein coding
8
coding regions
8
identification accuracy
8
proposed method
8

Similar Publications

Article Synopsis
  • Asthma causes inflammation and mucus buildup in the lungs, impacting airflow and making it difficult for orally or inhaled drugs to work effectively.
  • This study tested the diffusion of two asthma medications, theophylline and albuterol, through an artificial mucus layer, measuring their concentration over time using special spectroscopy techniques.
  • The results yielded diffusion coefficients for the drugs, which matched previous studies, and demonstrated a novel, non-invasive method to evaluate how well drugs can penetrate through complex mucus conditions.
View Article and Find Full Text PDF

Pulses in singularly perturbed reaction-diffusion systems with slowly mixed nonlinearity.

Chaos

November 2024

College of Mathematics and Statistics, Fujian Normal University, Fuzhou 350007, Fujian, People's Republic of China.

This article is concerned with the existence and spectral stability of pulses in singularly perturbed two-component reaction-diffusion systems with slowly mixed nonlinearity. In this paper, the slow nonlinearity is referred to be "mixed" in the sense that it is generated by a trigonometric function multiplied by a power function. We demonstrate via geometric singular perturbation theory that this model can support both the single-pulse and the double-hump solutions.

View Article and Find Full Text PDF

Pressure boundary conditions for immersed-boundary methods.

J Comput Phys

August 2024

Department of Mechanical and Aerospace Engineering, The George Washington University, 800 22nd Street NW, Washington DC, 20052, USA.

Immersed boundary methods have seen an enormous increase in popularity over the past two decades, especially for problems involving complex moving/deforming boundaries. In most cases, the boundary conditions on the immersed body are enforced via forcing functions in the momentum equations, which in the case of fractional step methods may be problematic due to: i) creation of slip-errors resulting from the lack of explicitly enforcing boundary conditions on the (pseudo-)pressure on the immersed body; ii) coupling of the solution in the fluid and solid domains via the Poisson equation. Examples of fractional-step formulations that simultaneously enforce velocity and pressure boundary conditions have also been developed, but in most cases the standard Poisson equation is replaced by a more complex system which requires expensive iterative solvers.

View Article and Find Full Text PDF

Objectives: The most critical step in the calculation of final limb length discrepancy (LLD) is estimating the length of the short limb after skeletal maturity(Sm). Paley's multiplier method is a fast, convenient method for calculating Sm and LLD after skeletal maturity; nonetheless, the calculation of the process of Sm and LLD in acquired type cases is complex in contrast to congenital type in this method. Notwithstanding, the multiplier method uses a variable called "growth inhibition" for the calculation process in acquired type LLD; however, its mathematical proof has not been published yet.

View Article and Find Full Text PDF

AbstractAnimals regulate their food intake to maximize the expression of fitness traits but are forced to trade off the optimal expression of some fitness traits because of differences in the nutrient requirements of each trait ("nutritional trade-offs"). Nutritional trade-offs have been experimentally uncovered using the geometric framework for nutrition (GF). However, current analytical methods to measure such responses rely on either visual inspection or complex models of vector calculations applied to multidimensional performance landscapes, making these approaches subjective or conceptually difficult, computationally expensive, and, in some cases, inaccurate.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!