AI Article Synopsis
- A female Caucasian patient presented with chronic eosinophilia and distinctive skin symptoms over several years, including hyperkeratotic papules and palmoplantar keratoderma.
- The patient also experienced generalized lymphadenopathy and increased total IgE levels.
- Diagnosed with pachydermatous eosinophilic dermatitis, she was treated with a combination of dapsone, oral methylprednisolone, and fexofenadine, resulting in significant improvement in her skin condition after one month.
Article Abstract
A case is presented of a female Caucasian patient with chronic peripheral blood eosinophilia and unusual skin manifestations. Within a couple of years, the patient developed multiple hyperkeratotic and hyperpigmented papules and plaques all over the body, palmoplantar keratoderma, pachydermia of acral parts of the body, and generalized pruritus. Generalized lymphadenopathy appeared. Other relevant symptoms were persistent peripheral blood hypereosinophilia and increased level of total IgE. The patient was diagnosed with a very rare condition, pachydermatous eosinophilic dermatitis, and was administered combined therapy with dapsone, oral methylprednisolone and fexophenadine. After one month of treatment, the skin changes markedly improved.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Pachydermatous eosinophilic dermatitis.
Acta Dermatovenerol Croat
August 2011
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Poland.
Article Synopsis
- A female Caucasian patient presented with chronic eosinophilia and distinctive skin symptoms over several years, including hyperkeratotic papules and palmoplantar keratoderma.
- The patient also experienced generalized lymphadenopathy and increased total IgE levels.
- Diagnosed with pachydermatous eosinophilic dermatitis, she was treated with a combination of dapsone, oral methylprednisolone, and fexofenadine, resulting in significant improvement in her skin condition after one month.
Pachydermatous eosinophilic dermatitis.
Br J Dermatol
March 1996
Department of Dermatology, University of Pretoria, Republic of South Africa.
We report three South African black teenage girls with extensive pruritic papular lesions arising on a pachydermatous base, resembling severe atopic dermatitis or onchodermatitis. All three had peculiar hypertrophic genital lesions and peripheral blood eosinophilia. Histological studies showed an eosinophil-rich lymphohistiocytic infiltrate and variable fibrosis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!