Three strains of mice were given, per os and ad libitum, a spa water containing 6.8 mg/l arsenic and indicated for the treatment of allergic respiratory diseases or chronic bronchitis. The daily arsenic intake was approximately from 1.5 to 4 mg/kg. No effect on body weight gain or on the various immune parameters assessed was observed. These results demonstrate that this spa water, despite its high arsenic content, is not toxic and does not interfere with the immune system of healthy mice.
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