Clindamycin in a commonly used antibiotic, considered safe for oral, intravenous and intra-arterial use. We present a case of a patient that received an inadvertent injection clindamycin 600 mg in 4 mL through a radial arterial line. The patient presented signs and symptoms of vascular occlusion and despite aggressive pharmacological and medical treatment developed massive and severe tissue injury.
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Retina
January 2025
L V Prasad Eye Institute, GMR Varalaxmi Campus, Visakhapatnam, Andhra Pradesh, India.
Purpose: To study the role of intravitreal clindamycin with dexamethasone as an adjuvant to systemic co-trimoxazole and steroids in macular Toxoplasma retinochoroiditis.
Methods: Retrospective study of Toxoplasma retinochoroiditis cases from January 2014 to December 2021 treated with a combination of oral and intravitreal therapy in immunocompetent patients.
Results: 39 eyes of 39 patients were included in this study after meeting the inclusion criteria with the mean age of presentation being 25.
Medicine (Baltimore)
November 2024
Department of Pharmacy, Baiyin Central Hospital, Baiyin, Gansu, China.
Rationale: It is imperative to be cautious about the potential systemic allergic reaction caused by the combined use of Qing Kailing Injection (QKI) and clindamycin as it may be life-threatening.
Patient Concerns: A 48-year-old female with a history of hypertension was admitted to a private hospital with a fever and cough. She was diagnosed with lung infection and received QKI infusion, followed by clindamycin infusion.
Polymers (Basel)
November 2024
Department of Chemical Engineering, Faculty of Engineering, Chulalongkorn University, Bangkok 10330, Thailand.
The porous particles prepared from composited calcium-ortho-phosphate (biphasic), Thai silk fibroin, gelatin, and alginate, with an organic to inorganic component ratio of 15.5:84.5, were tested for their abilities to control the release of the commercialized antibiotic solutions, clindamycin phosphate (CDP) and amikacin sulfate (AMK).
View Article and Find Full Text PDFPoult Sci
December 2024
Hebei Normal University Of Science & Technology, College of Animal Science and Technology, Qinhuangdao, Hebei, 066000, China. Electronic address:
Samples of four dead Larus vegae along the coast of Beidaihe, Qinhuangdao City, were identified by PCR amplification, multi-sequence site typing (MLST), and serum agglutination test. The drug resistance phenotype, drug resistance gene, and virulence gene were detected by the Kirby-Bauer (K-B) method and PCR method, and the pathogenicity of mice and pigeons was further tested. The phylogenetic tree was constructed by whole genome sequencing and bioinformatics analysis.
View Article and Find Full Text PDFRetin Cases Brief Rep
October 2024
Cleveland Clinic Cole Eye Institute, Cleveland, OH 44106.
Purpose: To describe the first case of Coccidioides posadasii endophthalmitis.
Methods: A 41-year-old man referred for acute retinal necrosis (ARN) failing 3 months of outpatient treatment was referred for further management. Three consecutive pars plana vitrectomies were required to identify C.
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