The Miconia genus is the most representative of the Melastomataceae family, and some species are commonly used in Brazilian folk medicine as anti-inflammatory agents. In this work we investigated the leaves from Miconia rubiginosa (Bonpl.) DC, using high-speed countercurrent chromatography, which yielded 11 substances (eight flavonoids, gallic acid, casuarictin, and schizandriside). Identification was achieved using nuclear magnetic resonance spectroscopy and high-performance liquid chromatography-circular dichroism-diode array detection analyses.
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http://dx.doi.org/10.1089/jmf.2010.0157 | DOI Listing |
Heliyon
March 2023
Laboratory of Neuroscience and Pharmacological Assays (LANEF), Department of Physiology (DFS), Federal University of Sergipe, São Cristóvão, 49100000, Brazil.
J Med Food
October 2011
Department of Organic Chemistry, Institute of Chemistry, São Paulo State University, Araraquara, São Paulo, Brazil.
The Miconia genus is the most representative of the Melastomataceae family, and some species are commonly used in Brazilian folk medicine as anti-inflammatory agents. In this work we investigated the leaves from Miconia rubiginosa (Bonpl.) DC, using high-speed countercurrent chromatography, which yielded 11 substances (eight flavonoids, gallic acid, casuarictin, and schizandriside).
View Article and Find Full Text PDFOecologia
July 2009
Departamento de Zoologia, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Mutagenesis
November 2008
Department of General Biology, Biological Sciences Center, Londrina State University, Londrina, Parana, Brazil.
The genus Miconia comprises approximately 1000 species belonging to the Melastomataceae family. Several crude plant extracts from Miconia and their isolated compounds have shown biological activities, such as analgesic and anti-neoplastic action; however, no studies concerning their effects on DNA are available. The present study aimed to evaluate, in vivo, the genotoxic and mutagenic effects of four species of plants from Miconia genus using the comet assay and micronucleus test.
View Article and Find Full Text PDFJ Med Food
March 2008
Department of Organic Chemistry, Institute of Chemistry, São Paulo State University, Araraquara, São Paulo, Brazil.
This work evaluated the antimicrobial activity of the methanol and chloroform extracts of the leaves of Miconia cabucu, Miconia rubiginosa, and Miconia stenostachya using the disc-diffusion method. The results obtained showed that the methanol extracts of the leaves of M. rubiginosa and M.
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