AI Article Synopsis
- The study compared hepatitis B vaccination responses in children with celiac disease using two immunization schedules.
- Both groups of celiac patients had a lower response rate (78.1%) compared to healthy controls (95.9%).
- No significant difference was found between the response rates of the two vaccination schedules in celiac patients.
Article Abstract
Background/aims: We aimed to compare the response rates to hepatitis B virus vaccination in the first year of life, using two different immunization protocols, in children with celiac disease.
Methods: Study Group 1 included patients with celiac disease who received 10 μg of hepatitis B vaccine intramuscularly at birth (0), 2 and 9-12 months of life. Group 2 included those who received hepatitis B vaccine at 0, 1 and 6 months of life. Healthy children were divided into two control groups according to the above schedules.
Results: The total study group included 64 patients and 49 healthy controls. Celiac patients were found to have lower response rates with respect to controls (78.1% vs. 95.9%, respectively). The difference in response rates in the two patient groups was not statistically significant.
Conclusions: The response rates of celiac patients to the two different hepatitis B vaccination schedules showed no statistically significant difference.
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Source |
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| http://dx.doi.org/10.4318/tjg.2011.0152 | DOI Listing |
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