We show that tomographic diffractive microscopy can be used for profilometry applications with high transverse resolution. We present an iterative reconstruction procedure, based on a rigorous wave scattering model, that permits us to retrieve the profile of rough metallic interfaces from the complex scattered field. The transversal resolution is subwavelength, and can even fall below the classical resolution limit if the profile is rough enough for multiple interactions to occur. Large profiles, with tens of wavelength size, can be investigated.
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http://dx.doi.org/10.1364/JOSAA.28.000576 | DOI Listing |
Sensors (Basel)
January 2025
College of Science and Technology, Ningbo University, Ningbo 315000, China.
The quality of surface morphology can reflect the electrical performance of silver-based contacts. Existing research on the correlation of morphological-electrical performance is based solely on empirical models from traditional visual inspections and only considers the impact of visually observable macro-textural features on electrical performance. However, the influence of micro-textural features on electrical performance should not be overlooked.
View Article and Find Full Text PDFEur J Pharm Biopharm
January 2025
Department of Pharmacy, University of Huddersfield, Huddersfield HD1 3DH UK. Electronic address:
Recent developments in pharmacogenetics have emphasised the importance of customised medication, driving interest in technologies like FDM 3D-printing for tailored drug delivery. FDM 3D-printing is a promising technique for the on-demand manufacturing of customised oral dosage forms, providing flexibility in terms of shape and size, dose and drug release profiles. This study investigates the fabrication and characterisation of 3D-printed oral dosage forms using PEO as the primary polymer and PEG 6 K as a plasticiser.
View Article and Find Full Text PDFVirulence
December 2025
Myunggok Medical Research Institute, College of Medicine, Konyang University, Daejeon, South Korea.
(Mab), a nontuberculous mycobacterium, is increasing in prevalence worldwide and causes treatment-refractory pulmonary diseases. However, how Mab rewires macrophage energy metabolism to facilitate its survival is poorly understood. We compared the metabolic profiles of murine bone marrow-derived macrophages (BMDMs) infected with smooth (S)- and rough (R)-type Mab using extracellular flux technology.
View Article and Find Full Text PDFJ Med Virol
January 2025
Laboratório de Morfologia e Morfogênese Viral, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz-Fiocruz, Rio de Janeiro, Brazil.
An unprecedented global outbreak caused by the monkeypox virus (MPXV) prompted the World Health Organization to declare a public health emergency of international concern on July 23, 2022. Therapeutics and vaccines for MPXV are not widely available, necessitating further studies, particularly in drug repurposing area. To this end, the standardization of in vitro infection systems is essential.
View Article and Find Full Text PDFJ Sex Res
January 2025
School of Psychology, University of Auckland | Waipapa Taumata Rau, Auckland, New Zealand.
The term "rough sex" is widely used, but it is not always clear what it means. Through exploring people's working definitions of "rough sex," we asked what they revealed about the underlying phenomenon it is applied to, and whether it is actually thing. Our online survey of 567 New Zealand respondents (73.
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