Whole-genome sequences of four Mycobacterium bovis BCG vaccine strains.

J Bacteriol

Microbial Genome Research Center, CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, People’s Republic of China.

Published: June 2011

Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only vaccine available against tuberculosis (TB). A number of BCG strains are in use, and they exhibit biochemical and genetic differences. We report the genome sequences of four BCG strains representing different lineages, which will help to design more effective TB vaccines.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133212PMC
http://dx.doi.org/10.1128/JB.00405-11DOI Listing

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