Summary: Network motifs in integrated molecular networks represent functional relationships between distinct data types. They aggregate to form dense topological structures corresponding to functional modules which cannot be detected by traditional graph clustering algorithms. We developed CyClus3D, a Cytoscape plugin for clustering composite three-node network motifs using a 3D spectral clustering algorithm.

Availability: Via the Cytoscape plugin manager or http://bioinformatics.psb.ugent.be/software/details/CyClus3D.

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btr182DOI Listing

Publication Analysis

Top Keywords

cytoscape plugin
12
network motifs
12
cyclus3d cytoscape
8
plugin clustering
8
motifs integrated
8
clustering
4
clustering network
4
integrated networks
4
networks summary
4
summary network
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!