Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1089/omi.2011.0017 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Wastewater metagenomics in Africa: Opportunities and challenges.
PLOS Glob Public Health
December 2024
The African Center of Excellence in Bioinformatics and Data-Intensive Sciences, the Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
The advent of metagenomics has dramatically expanded our understanding of microbial communities, particularly through the study of wastewater, which serves as a rich source of microbial data. In Africa, wastewater metagenomics presents unparalleled opportunities for public health monitoring, antimicrobial resistance (AMR) tracking, and the discovery of new microbial species and functions. Utilizing high-throughput sequencing (HTS) technologies, this method allows for direct analysis of nucleic acids from wastewater samples, providing a cost-effective and comprehensive approach for pathogen surveillance.
View Article and Find Full Text PDFLength of stay and its associated factors in the neonatal intensive care unit of Gadarif Hospital, Eastern Sudan: a retrospective study.
BMC Pediatr
December 2024
Department of Obstetrics and Gynecology, College of Medicine, Qassim University, Buraydah, Saudi Arabia.
Background: Attention is increasingly paid to length of stay (LOS) in neonatal intensive care units (NICUs) across countries. Few published data on neonatal LOS exist in Africa, where there is a high burden of neonatal morbidity and mortality. Thus, this study investigated the factors associated with neonatal LOS in the NICU of Gadarif Hospital, Eastern Sudan.
View Article and Find Full Text PDFSynergistic label-free fluorescence imaging and miRNA studies reveal dynamic human neuron-glial metabolic interactions following injury.
Sci Adv
December 2024
Department of Biomedical Engineering, Tufts University, 4 Colby St, Medford, MA 02155, USA.
Neuron-glial cell interactions following traumatic brain injury (TBI) determine the propagation of damage and long-term neurodegeneration. Spatiotemporally heterogeneous cytosolic and mitochondrial metabolic pathways are involved, leading to challenges in developing effective diagnostics and treatments. An engineered three-dimensional brain tissue model comprising human neurons, astrocytes, and microglia is used in combination with label-free, two-photon imaging and microRNA studies to characterize metabolic interactions between glial and neuronal cells over 72 hours following impact injury.
View Article and Find Full Text PDFblast2galaxy: a CLI and Python API for BLAST+ and DIAMOND searches on Galaxy servers.
Bioinform Adv
November 2024
Department of Breeding Research, Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Seeland, 06466, Germany.
Motivation: The Galaxy workflow system is an open-source platform supporting data-intensive research in life sciences, featuring a user-friendly web interface for complex analyses without extensive programming. It also offers a representational state transfer based API, enabling remote execution of specific tools. Galaxy supports similarity searches for nucleotide and amino acid sequences, with integrated tools like NCBI BLAST+ and DIAMOND.
View Article and Find Full Text PDFFoundation model for efficient biological discovery in single-molecule data.
Res Sq
October 2024
Single Molecule Analysis Group, Department of Chemistry, The University of Michigan, Ann Arbor, MI, USA.
Modern data-intensive techniques offer ever deeper insights into biology, but render the process of discovery increasingly complex. For example, exploiting the unique ability of single-molecule fluorescence microscopy (SMFM). to uncover rare but critical intermediates often demands manual inspection of time traces and iterative approaches that are difficult to systematize.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!