A single-molecule study of the inhibition effect of Naringenin on transforming growth factor-β ligand-receptor binding.

Chem Commun (Camb)

Beijing National Laboratory for Molecular Sciences, Institute of Chemistry, Key Laboratory of Molecular Nanostructures and Nanotechnology, Chinese Academy of Sciences, Beijing 100190, PR China.

Published: May 2011

With single-molecule fluorescence imaging and single-molecule force measurement, we have found that the natural compound Naringenin exerts an inhibition effect on TGF-β ligand-receptor interaction, the initial step of TGF-β signaling.

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Source
http://dx.doi.org/10.1039/c1cc10778jDOI Listing

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