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| http://dx.doi.org/10.1007/s12687-010-0029-6 | DOI Listing |
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Magnetoactive elastomer-based dynamic urethral support device for stress urinary incontinence.
Acta Biomater
January 2025
Texas A&M University, Department of Biomedical Engineering, College Station, TX, United States; Texas A&M University, Department of Materials Science and Engineering, College Station, TX, United States. Electronic address:
Stress urinary incontinence (SUI) is the involuntary leakage of urine in response to increased intra-abdominal pressure during episodes of exertion. A common treatment method for SUI is sling implantation underneath the urethra to provide support. Most current sling procedures, however, cannot adjust urethral tension postoperatively.
View Article and Find Full Text PDFUnlabelled: Probiotics offer therapeutic benefits by modulating the local microbiome, the host immune response, and the proliferation of pathogens. Probiotics have the potential to treat complex diseases, but their persistence or colonization is required at the target site for effective treatment. Although probiotic persistence can be achieved by repeated delivery, no biomaterial that releases clinically relevant doses of metabolically active probiotics in a sustained manner has been previously described.
View Article and Find Full Text PDFMacroplastique® for stress urinary incontinence lights up as a PET-avid urethral lesion: A case report.
Case Rep Womens Health
October 2024
Department of Urology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390, USA.
Macroplastique® is a periurethral bulking agent used for the treatment of female stress urinary incontinence. It is composed of polydimethylsiloxane macroparticles suspended in a polyvinylpyrolidone carrier to allow injection. The patient in this case report had increased 18F-FDG avidity on PET scan at the site of prior Macroplastique® injection.
View Article and Find Full Text PDFDaily and Weekly Urine Variations in Bacterial Growth Susceptibility in Postmenopausal Women With no History of Urinary Tract Infection: A Pilot Study.
Urology
December 2024
UT Southwestern Medical Center, Dallas, TX. Electronic address:
Objective: To evaluate bacterial growth in the bladder as a major virulence factor during urinary tract infections (UTIs), we assessed the variability of uropathogenic bacterial growth in urine samples over multiple timepoints from 3 postmenopausal women with no history of UTI.
Methods: Following IRB approval, postmenopausal women who never had a UTI provided mid-stream urine samples 3 times daily (8 a.m.
Optimizing Promoters and Subcellular Localization for Constitutive Transgene Expression in Marchantia polymorpha.
Plant Cell Physiol
September 2024
Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, UK.
Marchantia polymorpha has become an important model system for comparative studies and synthetic biology. The systematic characterization of genetic elements would make heterologous gene expression more predictable in this test bed for gene circuit assembly and bioproduction. Yet, the toolbox of genetic parts for Marchantia includes only a few constitutive promoters that need benchmarking to assess their utility.
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