Purpose: To report a case of bilateral posterior ischemic optic neuropathy (PION) in a patient with severe diabetic ketoacidosis (DKA).
Design: Observational case report.
Participant: A 35-year-old male who suffered bilateral visual loss during a severe episode of DKA.
Methods: Neuro-ophthalmological examination, neuroimaging consisting of a CT scan and MRI of the brain and orbits, as well as a MRA of brain vessels.
Results: Bilateral PION was diagnosed in a 35-year-old male with no light perception vision, who emerged from a coma caused by severe DKA. The patient developed optic nerve pallor in both eyes 4 weeks after the initial examination. Visual acuity with no light perception in both eyes remained unchanged after 6 months' follow-up.
Conclusions: Severe DKA can be complicated by bilateral PION, resulting in total blindness.
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http://dx.doi.org/10.1159/000325141 | DOI Listing |
Alzheimers Dement
December 2024
Sorbonne Université, Paris Brain Institute - Institut du Cerveau - ICM, Inserm U1127, CNRS UMR 7225, AP-HP - Hôpital Pitié-Salpêtrière, Paris, France.
Background: Anosognosia, a hallmark of Alzheimer's disease (AD), manifests as a gradual decline in disease awareness, yet its neural correlates remain unclear. This study investigates how amyloid accumulation, glucose hypometabolism and cortical atrophy relate to cognitive awareness across the AD continuum. Both the pathological processes and the brain regions involved were studied.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Strathclyde, Glasgow, United Kingdom.
Background: Psychotic symptoms (delusions and/or hallucinations) are among the most common and impactful neuropsychiatric symptoms that occur within Alzheimer's disease (AD): present in around half of AD patients, they are associated with increased distress for the individual and their families, poorer disease outcome, and greater risk of hospitalization and death. Using Random Forest analyses, aim of this study is to provide clarity on the value of neuroanatomical, neuropsychological, and neuropsychiatric features when predicting the presence of psychotic symptoms in AD.
Method: Data used in preparation for this study was obtained from the Alzheimer's Disease Neuroimaging Initiative database (adni.
Cureus
December 2024
Otorhinolaryngology Department, Unidade Local de Saúde de São João, Porto, PRT.
Objectives The aim of this anatomical study was to analyze distances and anatomical relations between the lower cranial nerves and important neck landmarks. Methods Anatomical study based on neck dissection in Thiel-embalmed cadavers. Anatomical relations and distances between the vagus (X), accessory (XI), and hypoglossal (XII) nerves and important neck landmarks were registered and compared.
View Article and Find Full Text PDFAm J Sports Med
January 2025
Department of Sports Medicine, Shanghai Sixth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Background: Arthroscopic repair with the biceps rerouting (BR) technique has been determined to lead to promising clinical and biomechanical outcomes for treating large-to-massive rotator cuff tears (LMRCTs). However, the in vivo effects of BR on glenohumeral kinematics during functional shoulder movements have not been fully elucidated.
Purpose: To investigate whether BR provides a better restoration of shoulder kinematics compared with conventional rotator cuff repair (RCR).
Eur Arch Otorhinolaryngol
January 2025
Department of Otolaryngology and Phoniatrics-Head and Neck Surgery, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Introduction: There are inconsistencies in how different endoscopic procedures to manage Bilateral Vocal Fold Immobility (BVFI) have been described in the literature. This limits our ability to compare functional outcomes. There is no unifying international terminology available that precisely describes the anatomical boundaries and extent of the different types of treatment.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!