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http://dx.doi.org/10.1136/hrt.2009.183624 | DOI Listing |
JAMA Netw Open
January 2025
School of Life Course and Population Sciences, King's College London, London, United Kingdom.
Importance: Reducing the burden of stroke is a public health priority. While higher stroke incidence among ethnic minority populations (defined in the context of this study as individuals who are not White) is well established, reports on ethnic inequalities in care or outcomes are conflicting and often limited to hospital-admitted patients and short-term outcomes.
Objective: To investigate ethnic differences in stroke care and outcomes up to 5 years after stroke and describe temporal trends and contributory factors.
Cardiovasc Res
December 2024
Department of Cardiology, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Aim: Microcalcification increases the vulnerability of plaques and has become an important driver of acute cardiovascular events in diabetic patients. However, the regulatory mechanisms remain unclear. DJ-1, a multifunctional protein, may play a potential role in the development of diabetic complications.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Clinical Neuroscience Institute, King's College London, London, UK.
Background: Alzheimer's disease (AD) is a devastating disease at an individual level and for the wider society. Despite huge research efforts the underlaying causes of AD is still not well understood. We know that lipid metabolism is fundamental for maintaining a heathy brain and that some of the strongest risk factors for AD, such as APOE4, affect lipids.
View Article and Find Full Text PDFBackground: Alzheimer's disease and type 2 diabetes mellitus rank among the top ten leading global causes of death. The association between diabetes and Alzheimer's is linked to chronic low-grade inflammation, hyperinsulinemia, and the interplay between peripheral and central insulin resistance, influencing insulin signalling. We evaluated the association between diabetes and Alzheimer's-related neuropathology in cognitively unimpaired older adults with diabetes.
View Article and Find Full Text PDFFront Microbiol
December 2024
Department of Life Sciences, University of Science and Technology of Hanoi, Vietnam Academy of Science and Technology, Hanoi, Vietnam.
Background: Colorectal cancer (CRC) is among the top three causes of global cancer mortality. In Vietnam, CRC is the third leading cause of death in women and the fourth cause of cancer mortality in men. A large number of metagenomic studies have reported the relationship between altered composition and function of the gut microbiota with CRC, but this relationship in low- and middle-income countries including Vietnam (with an estimated population of 100.
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