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Differential effect of nonpharmacological interventions according to prediabetes phenotype: Systematic review and meta-analysis of randomized clinical trials.
Diabet Med
January 2025
Universidad Científica del Sur, Lima, Peru.
Background And Aims: Impaired glucose intolerance (IGT) and impaired fasting glucose (IFG) are totally different. Lifestyle modification is effective in moving from prediabetes to normoglycaemia. There is a lack of information showing the effect of lifestyle modification according to each prediabetes and assessing its effect on the degree of reversibility to normoglycaemia and on cardiometabolic markers.
View Article and Find Full Text PDFEquality and diversity in research: building an inclusive future.
BMC Res Notes
January 2025
Department of General Surgery, The Royal Marsden Hospital, London, UK.
Research progress and innovation are hindered by barriers, inequalities, and exclusions within academia. Embracing equality, diversity, and inclusion (EDI) is not only an ethical imperative but also essential for advancing knowledge and addressing global challenges. EDI principles ensure that researchers from all backgrounds have equitable opportunities to contribute to and benefit from research.
View Article and Find Full Text PDFOptimal allocation of antenatal and young child nutrition interventions: an individual-based global burden of disease calibrated microsimulation.
BMC Glob Public Health
January 2025
Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Background: Undernutrition remains a global crisis and is a focus of Sustainable Development Goals. While there are multiple known, effective interventions, complex interactions between prevention and treatment and resource constraints can lead to difficulties in allocating funding. Simulation studies that use in silico simulation can help illuminate the interactions between interventions and provide insight into the cost-effectiveness of alternative packages of options.
View Article and Find Full Text PDFMultiChem: predicting chemical properties using multi-view graph attention network.
BioData Min
January 2025
Department of Computer Science, Hanyang University, Seoul, Republic of Korea.
Background: Understanding the molecular properties of chemical compounds is essential for identifying potential candidates or ensuring safety in drug discovery. However, exploring the vast chemical space is time-consuming and costly, necessitating the development of time-efficient and cost-effective computational methods. Recent advances in deep learning approaches have offered deeper insights into molecular structures.
View Article and Find Full Text PDFEvaluating catastrophic health expenditures among patients with long bone fractures in Ghana's major teaching hospitals: a hospital-based analysis.
BMC Health Serv Res
January 2025
AO Alliance, Stiftung, Switzerland.
Background: In low and middle-income countries like Ghana, out-of-pocket (OOP) payments remain a significant barrier to healthcare access, often leading to catastrophic health expenditures (CHE). This study evaluates the incidence of CHE among patients treated for long bone fractures at Ghana's major teaching hospitals, providing insight into the economic burdens faced by these patients.
Methods: This cross-sectional study analyzed data from 2,980 patients with long bone fractures treated at four major teaching hospitals in Ghana from July 2017 to July 2020.
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