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An insight into the applications of bacteriophages against food-borne pathogens.
J Food Sci Technol
January 2025
Department of Genetic Engineering, Faculty of Engineering and Technology, School of Bioengineering, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, Kanchipuram, Chennai, Tamil Nadu 603203 India.
Novel and emerging pathogens, enduring contamination, antibiotic resistance, an environment that is always changing, and the complexity of food production systems all contribute to the worsening of foodborne illness. It has been proposed that bacteriophages can serve as both fast food-borne pathogen detection tools and natural food preservatives in a variety of foods. Phages, like many other antimicrobial interventions used in food production systems, are not a cure-all for issues related to food safety, though.
View Article and Find Full Text PDFAntimicrobial Resistance Patterns of Clinically Isolated Strains of Acinetobacter baumannii in a Tertiary Care Hospital in Libya.
Cureus
December 2024
Department of Genetic Engineering, Libyan Biotechnology Research Center, Tripoli, LBY.
Objective: accounts for a notable percentage of hospital-acquired infections. The widespread resistance to multiple antibiotic classes complicates treatment efforts. This study aims to find out the pattern of susceptibility of multidrug-resistant (MDRAB) isolated from clinical specimens to antibiotics recommended for testing and use for and to determine a local guide at Tripoli University Hospital (TUH), Tripoli, Libya for the empirical antibiotic treatment of MDRAB based on the susceptibility pattern identified.
View Article and Find Full Text PDFEvaluating the Role of KRAS and NRAS 3' Untranslated Region Polymorphisms in Susceptibility and Clinical Features of Laryngeal Squamous Cell Carcinoma.
Cureus
December 2024
Medical Biotechnology, National Institute of Genetic Engineering and Biotechnology, Tehran, IRN.
Laryngeal squamous cell cancer (LSCC) is one of the most common head and neck cancers in which genetic factors play an important role in its occurrence. This study investigated the association of and gene polymorphisms with the risk of LSCC. polymorphisms including rs712, rs61764370, rs8720, and rs9266, as well as NRAS rs14804, were compared in the patient group (n=120) and the control group (n=100).
View Article and Find Full Text PDFRapid introgression of the clubroot resistance gene into cabbage skeleton inbred lines through marker assisted selection.
Mol Breed
February 2025
Key Laboratory of Biology and Genetic Improvement of Horticultural Crops, Ministry of Agriculture, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, 100081 China.
Unlabelled: Clubroot, caused by , is a globally pervasive soil-borne disease that poses a significant challenge primarily in cruciferous crops. However, the scarcity of resistant materials and the intricate genetic mechanisms within cabbage present major obstacles to clubroot resistance (CR) breeding. In our previous research, we developed an Ogura CMS cabbage variety, "17CR3", which harbors the gene, crucial for CR.
View Article and Find Full Text PDFStem cell-derived exosome delivery systems for treating atherosclerosis: The new frontier of stem cell therapy.
Mater Today Bio
February 2025
Institute of Optical Functional Materials for Biomedical Imaging, School of Chemistry and Pharmaceutical Engineering, Shandong First Medical University & Shandong Academy of Medical Science, Taian, Shandong, 271016, PR China.
Cardiovascular diseases (CVDs) are a leading cause of mortality worldwide. As a chronic inflammatory disease with a complicated pathophysiology marked by abnormal lipid metabolism and arterial plaque formation, atherosclerosis is a major contributor to CVDs and can induce abrupt cardiac events. The discovery of exosomes' role in intercellular communication has sparked a great deal of interest in them recently.
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