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Aerobic bacteria study, clinical spectrum, and outcome of patients with community-acquired multidrug-resistant pathogens.
J Family Med Prim Care
November 2024
Consultant Clinical Microbiologist, Department of Laboratory Medicine, KIMS SAVEERA Hospital, Anantapur, Andhra Pradesh, India.
Context: Infectious diseases are the leading cause of death in developing countries like India. Hence, even small relative increases in the mortality rate for infections due to multidrug-resistant pathogens would lead to substantial increases in the number of deaths as a result of infections worldwide.
Aims: The aim of the study was to study the microbiological data of community-acquired pathogens and the corresponding outcomes due to antibiotic-resistant versus antibiotic-susceptible bacterial microorganisms.
Analysis of clinical characteristics and mortality risk factors in patients with community-acquired pneumonia caused by Klebsiella pneumoniae.
Diagn Microbiol Infect Dis
December 2024
Department of Clinical Microbiology, Pulmonary and Critical Care Medicine, Zibo City Key Laboratory of Respiratory Infection and Clinical Microbiology, Zibo City Engineering Technology Research Center of Etiology Molecular Diagnosis, Zibo Municipal Hospital, Zibo 255400, China. Electronic address:
Community-acquired pneumonia (CAP) caused by Klebsiella pneumoniae (KP) results in high mortality. 121 cases were included in this study to explore the characteristics and risk factors of CAP patients caused by hypervirulent or resistant KP strains, which were limited reported in previous studies. We found that neither hypervirulent KP nor ESBL-producing KP infections affect mortality (P > 0.
View Article and Find Full Text PDFTwo rare cases of severe community-acquired bloodstream infections: a clinical case report.
Front Immunol
December 2024
Department of Intensive Care Unit, Peking University International Hospital, Beijing, China.
Background: The escalating demographic shift towards an aging population and the widespread occurrence of immunological diseases have contributed to an elevation in the frequency of community-acquired infections. Notably, among these infections, community-acquired bloodstream infections (CABSI) stand out due to their significant lethality. Detailed medical history inquiries, assessment of underlying immune status, detection of the source of infection, and initial precise identification and treatment of the infectious agents can improve the prognosis of CABSI.
View Article and Find Full Text PDFCommunity-Acquired Pneumonia in Adults: A Mono-Center Retrospective Study.
Tanaffos
January 2024
Department of Radiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Adult community-acquired pneumonia is the most common cause of hospitalization and a leading cause of death. Identification of microorganisms causing community-acquired pneumonia.
Materials And Methods: A cross-sectional design was used.
Emergence of -bearing MDR-hypervirulent ST307.
Microbiol Spectr
December 2024
School of Biomedical Sciences, University of West London, London, United Kingdom.
We report for the first time whole-genome sequencing of four multidrug-resistant sequence type (ST) 307 recovered from patients in two hospitals in Armenia. Comparative genomic analysis revealed that the isolates were closely related, with a maximum of 39 single nucleotide polymorphism (SNP) differences in the core genome. All Armenian isolates carried the integrative and conjugative element ICE4, which bears the yersiniabactin locus, and shared a common evolutionary origin, diverging around 2005 (95% CI: 1999 to 2011).
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