AI Article Synopsis
- Digital ulcers (DUs) and gangrene are frequent skin issues in connective tissue diseases like systemic sclerosis, with 95% of patients experiencing Raynaud's phenomenon (RP), leading to DUs in about 30%.
- While RP is common in various conditions, DUs are rare in systemic lupus erythematosus (SLE) and don't typically appear at disease onset.
- This case report highlights a young woman where DUs were the first sign of SLE, along with indications of a scleroderma pattern and high pulmonary arterial pressure.
Article Abstract
Digital ulcers (DUs) and gangrene are common skin manifestations of connective tissue diseases, especially systemic sclerosis. Raynaud's phenomenon (RP) is an almost universal manifestation of systemic sclerosis, with 95% of all patients being affected, and resulting in DUs in approximately 30% of the patients each year. Although RP may be present in approximately 25-50% of the patients, DUs are relatively rare in systemic lupus erythematosus (SLE) and never present as an initial manifestation of disease. In this case report DUs appear as the initial manifestation of SLE in a young woman with a capillaroscopic scleroderma pattern and elevated systolic pulmonary arterial pressure.
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| http://dx.doi.org/10.2169/internalmedicine.50.4617 | DOI Listing |
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