Traumatic injury of the pancreas is rare in children. It is often difficult to diagnose due to the lack of signs and symptoms, and shortly after trauma laboratory values may be normal. In addition, ultrasound and CT are often not specific. The treatment of grade 1 and 2 injury is non-operative. Although there seems to be a shift towards non-operative management of grade 3-5 injuries (with injury of the pancreatic duct), this is still a matter of debate. We describe 3 children, a girl of 2.5 years-old and a boy of 7 years-old, with grade 3 pancreatic injuries and an 8-year-old boy with a grade 2 injury. We demonstrate that the diagnosis is hard to establish, while the consequences of this injury can be serious. Thinking of pancreatic injury is most important to its diagnosis. We advocate referral to or consultation of specialized centres in these cases.
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J Pediatr Hematol Oncol
January 2025
Centers for Cancer and Blood Disorders and Cancer and Immunology Research, Children's National Hospital.
Children with T-ALL/LBL require prompt diagnosis and treatment. Flow cytometric analysis of T-lineage and immaturity markers usually leads to a straightforward diagnosis. However, rare cases of T-ALL expressing bright CD45 and lacking expression of immature markers can be a diagnostic conundrum and difficult to differentiate from mature T-cell lymphomas lacking surface CD3 expression or aberrantly expressing immature markers, which affects treatment decisions and prognosis.
View Article and Find Full Text PDFFront Robot AI
December 2024
Robot Learning Laboratory, Instituto de Ciências Matemáticas e de Computação (ICMC), University of São Paulo (USP), SãoCarlos, Brazil.
Research on social assistive robots in education faces many challenges that extend beyond technical issues. On one hand, hardware and software limitations, such as algorithm accuracy in real-world applications, render this approach difficult for daily use. On the other hand, there are human factors that need addressing as well, such as student motivations and expectations toward the robot, teachers' time management and lack of knowledge to deal with such technologies, and effective communication between experimenters and stakeholders.
View Article and Find Full Text PDFArch Razi Inst
June 2024
Department of Biomedical Sciences, College of Medicine, University of Zakho, Kurdistan Region, Iraq.
Intestinal protozoan parasitic infections are considered one of the most frequent types of infection caused by these parasites and remain a major health problem for communities. This study aims to detect the frequency of intestinal protozoan infections infection among Zakho general population from October 2018 to June 2022. This cross-sectional study was performed on 2,118 patients referring to private medical diagnostic laboratories in Zakho, Kurdistan Region, Iraq.
View Article and Find Full Text PDFChest
December 2024
Children's Hospital of Orange County, University California, Irvine, Orange County, Calif.
The small airways comprise generations 8 to 23 of the bronchial tree, consist of airways with an internal diameter <2mm, and are classically difficult to assess and treat in persistent asthma. Small airways dysfunction (SAD) is integral to the asthma management paradigm as it is associated with poorer symptom control, greater levels of type 2 inflammation, and has been proposed as a potential treatable asthma trait. Although identification of SAD by oscillometry has been found to be clinically useful in managing asthma, very few physicians, including specialists, use this technique as part of standard or adjunct evaluation of lung function to diagnose asthma, grade severity of airway obstruction, ascertain disease control or the risk for future exacerbations or to make management decisions.
View Article and Find Full Text PDFInt J Infect Dis
December 2024
PandemiX Center, Dept of Science & Environment, Roskilde University, Roskilde, Denmark. Electronic address:
The recent expansion of mpox in Africa is characterized by a dramatic increase in zoonotic transmission (clade Ia) and the emergence of a new clade Ib that is transmitted from human-to-human (H2H) by close contact. Clade Ia does not pose a threat in areas without zoonotic reservoir. But clade Ib may spread widely, as did the clade IIb that since 2022 has spread globally among MSM.
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