Purpose: To report 2 cases of keratopathy after uneventful cross-linking procedures for grade 3 keratoconus.
Methods: Two patients (21 and 11 years old) with grade 3 keratoconus underwent uneventful cross-linking in 1 eye. In both patients, multiple peripheral stromal precipitates, which extended centripetally, were observed 48 hours after the procedure. Sample cultures were negative for bacteria, fungi, and parasites.
Results: Cornea infiltrates slowly resolved after combined topical antibiotic/antifungal/povidone/steroids treatment. Final best spectacle-corrected visual acuity was 20/25 for patient 1, after uneventful bilateral toric intraocular contact lens (ICL) (Staar Surgical) implantation, but faint and paracentral scarring persisted. Final best-corrected visual acuity was 20/25 for patient 2 with gas-permeable contact lens wear, despite stromal scarring.
Conclusions: Cross-linking associated with sterile keratitis is an unusual entity of unknown etiology, which can lead to stromal scarring.
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http://dx.doi.org/10.1097/ICO.0b013e3182096789 | DOI Listing |
Oman J Ophthalmol
October 2024
Cornea and Anterior Segment, Shantilal Shanghvi Cornea Institute, L V Prasad Eye Institute, Vijayawada, Andhra Pradesh, India.
In this case series, we will describe sterile keratitis in the early postoperative period after hypotonic collagen cross-linking (CXL) in two pediatric cases. This is a retrospective case series of two eyes of two children who developed inflammatory keratitis with central corneal haze after uneventful epithelial-off hypotonic CXL. After ensuring microbiological sterility, appropriate treatment with topical steroids and lubricants was started.
View Article and Find Full Text PDFEur J Ophthalmol
September 2023
Key NHC Key Laboratory of Myopia (Fudan University); Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China.
Purpose: To investigate the long-term clinical outcomes and changes in crystalline lens transparency after accelerated (45 mW/cm) transepithelial corneal cross-linking (ATE-CXL) using the Pentacam imaging system in patients with progressive keratoconus.
Methods: The study prospectively included 44 keratoconus eyes of 40 patients (mean age: 24.39 ± 5.
J Clin Med
October 2022
Department of Ophthalmology, American University of Beirut Medical Center, Beirut 1107, Lebanon.
We aimed to evaluate the depth of the demarcation line following accelerated epithelium-off corneal cross-linking (A-CXL) performed at the slit lamp with the patient sitting in an upright position. Twenty-three eyes from twenty patients, undergoing epi-off A-CXL (9 mW/cm for 10 min) using a CXL device at the slit lamp in the upright position. Demarcation line depth was assessed at 1 month after the procedure using anterior segment optical coherence tomography (AS-OCT) and specialized software.
View Article and Find Full Text PDFAm J Case Rep
July 2022
Department of Ophthalmology, Hospital Angeles Chihuahua, Chihuahua, Mexico.
BACKGROUND Acute corneal hydrops refers to a rare complication of keratoconus and other ectatic disorders with potentially sight-threatening sequelae. Intrastromal corneal ring segment (ICRS) implantation is a surgical procedure performed as therapy for keratoconus when there is contact lens intolerance. ICRS migration along the tunnel made for its insertion is one of its most frequent complications.
View Article and Find Full Text PDFEur J Ophthalmol
September 2022
Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Tirunelveli, Tamil Nadu, India.
A 26-year-old female presented to us with complaints of progressive loss of vision in right eye (RE) since past 6 months. Patient was a known case of generalized systemic sclerosis with hypothyroidism for the past 2 years and was under treatment with a rheumatologist Physical features of scleroderma seen in her included diffuse skin tightness, hyper pigmentation of skin of face, abdomen, thighs, legs and arms, with ulcers on fingers. Her best corrected visual acuity was 20/320 in the RE and 20/20 in the left eye (LE).
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