Background And Purpose: Invasive methods are more reproducible and accurate than non-invasive ones when it comes to recording knee kinematics, but they are usually less accessible and less safe, mainly due to risk of infection. For this reason, non-invasive methods with passive markers are widely used. With these methods, varying marker sets based on a number of single markers, or sets of markers, known as clusters, are used to track body segments. We compared one invasive method--radiostereometric analysis--with a non-invasive method, an optical tracking system with 15 skin-mounted markers.
Methods: 9 subjects (10 knees) were investigated simultaneously with a dynamic RSA system and a motion-capture system while performing an active knee extension.
Results: For flexion/extension, there was good agreement on an individual basis and at the group level. For internal/external rotation, the group mean was fairly similar, up to 25 degrees of flexion. Recordings of abductions and/or adductions revealed a systematic mean difference of 2-4 degrees during the range of flexion measured. The correlation between the 2 methods in the horizontal and frontal planes was poor.
Interpretation: Our skin-marker model provided reliable data for flexion/extension. Recordings of internal/external rotation and abduction/adduction were less accurate on an individual basis than at the group level, most probably due to soft-tissue motion and the presence of small true motion in these planes.
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http://dx.doi.org/10.3109/17453674.2011.570675 | DOI Listing |
Clin Neurophysiol
January 2025
Institute of Neuroscience (IoNS), Catholic University of Louvain, Brussels, Belgium; Walloon Excellence in Life Sciences and Biotechnology (WELBIO) Department, WEL Research Institute, Avenue Pasteur 6, 1300 Wavre, Belgium; Center for Refractory Epilepsy, Department of Neurology, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Purpose: The Locus Coeruleus (LC) plays a vital role by releasing norepinephrine, which contributes to the antiepileptic effects of Vagus Nerve Stimulation (VNS). LC activity also influences pupil dilation. Investigating VNS dose-dependent Pupillary Dilation Response (PDR) may provide novel neurophysiological insights into therapeutic response and allow for an objective and personalized optimization of stimulation parameters.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Biomedical Engineering, Duke University, Durham, NC, USA.
Acoustically probing biological tissues with light or sound, photoacoustic and ultrasound imaging can provide anatomical, functional, and/or molecular information at depths far beyond the optical diffusion limit. However, most photoacoustic and ultrasound imaging systems rely on linear-array transducers with elevational focusing and are limited to two-dimensional imaging with anisotropic resolutions. Here, we present three-dimensional diffractive acoustic tomography (3D-DAT), which uses an off-the-shelf linear-array transducer with single-slit acoustic diffraction.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Center for Physical Sciences and Technology, Saulėtekio av.3, 10257 Vilnius, Lithuania.
Understanding the dynamics of injected charge carriers is crucial for the analysis of the perovskite light-emitting diode (PeLED) operation. The behavior of the injected carriers largely dictates the external quantum efficiency (EQE) roll-off at high current densities and the temperature dependence of the EQE in PeLEDs. However, limitations such as sample capacitance and external circuitry hinder precise control of carrier injection rates, making it challenging to directly track the dynamics of individual carriers.
View Article and Find Full Text PDFJ Vis
January 2025
Smith Kettlewell Eye Research Institute, San Francisco, CA, USA.
Macular degeneration (MD), which affects the central visual field including the fovea, has a profound impact on acuity and oculomotor control. We used a motion extrapolation task to investigate the contribution of various factors that potentially impact motion estimation, including the transient disappearance of the target into the scotoma, increased position uncertainty associated with eccentric target positions, and increased oculomotor noise due to the use of a non-foveal locus for fixation and for eye movements. Observers performed a perceptual baseball task where they judged whether the target would intersect or miss a rectangular region (the plate).
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Coating biological membranes onto biomimetic nanocarriers improves biocompatibility, prolongs circulation, and enhances targeted delivery for cancer precision medicine. To better understand the biodistribution profiles of these biomimetic nanosystems, molecular imaging techniques, including optical imaging, radionuclide imaging, magnetic resonance imaging, and ultrasound imaging, have been widely employed for in vivo tracking and dynamic imaging. Here in this review, we delve into the profound role of these imaging modalities in visualizing changes in the tumor microenvironment, particularly in monitoring oxygen consumption and immune response dynamics, highlighting their potential to improve cancer therapies.
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