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Age-related unstable transient states and imbalanced activation proportion of brain networks in people with autism spectrum disorder: A resting-state fMRI study using coactivation pattern analyses.
Netw Neurosci
December 2024
McLean Imaging Center, McLean Hospital, Harvard Medical School, Belmont, MA, USA.
The atypical static brain functions related to the executive control network (ECN), default mode network (DMN), and salience network (SN) in people with autism spectrum disorder (ASD) has been widely reported. However, their transient functions in ASD are not clear. We aim to identify transient network states (TNSs) using coactivation pattern (CAP) analysis to characterize the age-related atypical transient functions in ASD.
View Article and Find Full Text PDFBeyond Classification: A Unique Case of Self-Resolving Cutaneous Mucinosis Associated With Streptococcal Infection in a Child.
Pediatr Dermatol
December 2024
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months.
View Article and Find Full Text PDFRadiographs in Pediatric Rheumatology: Where Do We Stand?
Indian J Radiol Imaging
January 2025
Division of Paediatric Rheumatology, Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Article Synopsis
- Rheumatic disorders in children encompass a range of conditions including inflammatory arthritis, bone disorders like chronic nonbacterial osteomyelitis (CNO), connective tissue disorders, and vasculitides (e.g., juvenile dermatomyositis, scleroderma).
- Diagnosis relies on patient history, clinical exams, lab tests, and importantly, radiographs help identify issues in atypical cases and assess disease damage.
- The review provides an in-depth look at when to use radiographs and their benefits, along with a structured reporting format for evaluating these images in pediatric rheumatic disorders.
New onset heart failure in adolescents with inflammatory joint disease treated with TNF-α inhibitors: a case-based review.
Rheumatol Int
December 2024
Division of Pediatric Rheumatology, Department of Pediatrics, Attikon General Hospital, National and Kapodistrian University of Athens, Athens, Greece.
The safety of tumor necrosis factor (TNF) inhibitors has been demonstrated for over two decades. However, their effects on cardiovascular function in patients with rheumatic diseases remain controversial, and conclusions are additionally hampered by the cardiovascular complications inherent in such diseases. We present two 15-year-old patients diagnosed with ankylosing spondylitis and juvenile idiopathic arthritis classified as polyarthritis with positive rheumatoid factor, respectively.
View Article and Find Full Text PDFNeurofibromatosis Type 2 Presenting as Symptomatic Gallbladder Hydrops: A Rare Case Report and Literature Review.
Case Rep Pediatr
November 2024
Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.
Article Synopsis
- * A case study of a 12-year-old girl revealed NF2 when she presented with abdominal pain, leading to the discovery of a benign nerve sheath tumor in her gallbladder that mimicked atypical symptoms.
- * This case highlights the importance of recognizing uncommon manifestations of NF2 for early diagnosis and treatment, and it emphasizes the need for a collaborative approach in patient management.
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