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Impact of Dosimetric Compromises on Early Outcomes of Chordomas and Chondrosarcomas Treated With Image-guided Pencil Beam Scanning Proton Beam Therapy.
Adv Radiat Oncol
October 2024
Department of Radiation Oncology, Apollo Proton Cancer Centre, Chennai, Tamil Nadu, India.
Purpose: To critically review the clinical factors, dosimetry, and their correlation with early outcomes in patients with chordomas and chondrosarcomas treated with pencil beam scanning (PBS) proton beam therapy (PBT).
Methods And Materials: Consecutive 64 patients diagnosed with chordoma or chondrosarcoma treated at our center were studied. Patient, tumor, and treatment-related factors including dosimetry were captured.
Combining morphological and functional imaging parameters to diagnose primary bone neoplasms in the skull base, spine and sacrum.
Skeletal Radiol
February 2025
Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.
Purpose: Morphological magnetic resonance (MR) and computed tomography (CT) features are used in combination with histology for diagnosis and treatment selection of primary bone neoplasms. Isolated functional MRI parameters have shown potential in diagnosis. Our goal is to facilitate diagnosis of primary bone neoplasms of the skull base, mobile spine and sacrum, by a comprehensive approach, combining morphological and functional imaging parameters.
View Article and Find Full Text PDFSoft Tissue Reconstruction After Sacral Neoplasm Resection: The University of California San Francisco Experience.
Ann Plast Surg
May 2024
Department of Surgery, Division of Plastic and Reconstructive Surgery, University of California San Francisco, San Francisco, CA.
Purpose: Resection of sacral neoplasms such as chordoma and chondrosarcoma with subsequent reconstruction of large soft tissue defects is a complex multidisciplinary process. Radiotherapy and prior abdominal surgery play a role in reconstructive planning; however, there is no consensus on how to maximize outcomes. In this study, we present our institution's experience with the reconstructive surgical management of this unique patient population.
View Article and Find Full Text PDFComposite Reconstruction With Irradiated Autograft Plus Total Hip Replacement After Type II Pelvic Resections for Tumors Is Feasible but Fraught With Complications.
Clin Orthop Relat Res
October 2024
Department of Orthopedics and Traumatology, Ege University School of Medicine, Izmir, Turkey.
Background: Malignancies involving the pelvic ring present numerous challenges, especially in the periacetabular area. Extensive resection of the pelvic region without reconstruction can lead to severe functional impairment. Numerous reconstructive options exist, but all have drawbacks.
View Article and Find Full Text PDF[Surgical margins as prognostic factor in pelvis chondrosarcoma. Cohort study in a sarcoma unit].
Acta Ortop Mex
March 2024
Departamento de Piel, Partes Blandas y Tumores Óseos. Instituto Nacional de Cancerología (México).
Introduction: chondrosarcoma is the second most common primary malignant tumor, constitutes approximately one quarter of all primary bone sarcomas. Surgical margins in pelvic chondrosarcoma have a direct impact as a prognostic factor, both on overall survival and on recurrence-free survival of this disease.
Objectives: to analyze the impact of surgical margins as a prognostic factor in pelvic chondrosarcoma.
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