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Plasmon-Driven Gold Nanopillar Multiarrayed Gene Amplification Methodology for the High-Throughput Discrimination of Pathogens.
Adv Sci (Weinh)
January 2025
SKKU Advanced Institute of Nanotechnology (SAINT), Sungkyunkwan University, Suwon, 16419, South Korea.
Molecular diagnosis limitations, including complex treatment processes, low cost-effectiveness, and operator-dependent low reproducibility, interrupt the timely prevention of disease spread and the development of medical devices for home and outdoor uses. A newly fabricated gold nanopillar array-based film is presented for superior photothermal energy conversion. Magnifying the metal film surface-to-volume ratio increases the photothermal energy conversion efficiency, resulting in a swift reduction in the gene amplification reaction time.
View Article and Find Full Text PDFExploring tele-speech therapy: A scoping review of interventions, applications, benefits, and challenges.
Int J Med Inform
January 2025
Artificial Intelligence in Medical Sciences Research Center , Smart University of Medical Sciences, Tehran, Iran; Department of Artificial Intelligence, Smart University of Medical Sciences, Tehran, Iran. Electronic address:
Background: Speech disorders can significantly impact communication, social interaction, and overall quality of life, affecting individuals of all ages. Telespeech therapy has emerged as an innovative solution, leveraging technology to provide accessible and effective speech interventions remotely. This approach offers flexibility and convenience, addressing barriers such as geographical limitations and scheduling conflicts.
View Article and Find Full Text PDFModeling and the Use of Surrogate Endpoints: Is This a Valid Approach?
Dig Dis Sci
January 2025
Department of Public Health, Erasmus University Medical Center, Rotterdam, Netherlands.
Background: Development of novel colorectal cancer (CRC) screening tests is a dynamic field. Decision analytic modeling based on inputs derived from rigorous prospective studies informs CRC screening guidelines. Exploratory modeling may have a place in early phases of test development.
View Article and Find Full Text PDFEconomic evaluation of newborn screening for congenital cytomegalovirus infection: A systematic review.
Eur J Pediatr
January 2025
Division of Policy Evaluation, Department of Health Policy, Research Institute, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-Ku, Tokyo, 157-8535, Japan.
Purpose: This systematic review analyzes economic evaluations of newborn screening for congenital cytomegalovirus (cCMV) infection to identify key factors influencing cost-effectiveness and differences in methodological approaches.
Methods: Following a pre-registered PROSPERO protocol (CRD42023441587), we conducted a comprehensive literature search across multiple databases on July 4, 2024. The review included both full economic evaluations (cost and outcomes) and partial economic evaluations (cost only).
The valuation of older adult homecare services under a joint medical-social budgetary perspective.
Front Public Health
January 2025
Department of Management Sciences, City University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Background: Homecare, a cornerstone of public health, is essential for health systems to achieve the Sustainable Development Goal (SDG) of universal health coverage while maintaining its own sustainability. Notwithstanding homecare's system-level significance, there is a lack of economic evaluations of homecare services in terms of their system-wide cost-savings. Specifically, decisions informed by a joint medical-social budgetary perspective can maximize the allocative efficiency of assigning a diverse service mix to address the complex needs of the older adult population.
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