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Breastfeeding and infant growth in relation to childhood overweight - A longitudinal cohort study.
Am J Clin Nutr
January 2025
Dept. of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark; Steno Diabetes Center Aarhus, Aarhus University Hospital, Palle Juul-Jensens Boulevard 11, 8200 Aarhus N, Denmark.
Background: Rapid infant growth is positively, and breastfeeding inversely, associated with childhood overweight. However, the interplay has only been sparsely investigated.
Objective: We aimed to investigate how exclusive breastfeeding duration modify the effect of infant growth on childhood overweight.
Maternal and Infant Characteristics and Pumping Profiles of Women That Predominantly Pump Milk for Their Infants.
Nutrients
January 2025
School of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Background: Whilst it is inconvenient and time-intensive, predominantly (PP) and exclusively pumping (EP) mothers rely on breast expression to provide milk for their infants and to ensure continued milk supply, yet these populations are poorly understood.
Methods: We assessed and characterised Western Australian PP mothers ( = 93) regarding 24 h milk production (MP) and infant milk intake and demographics, perinatal complications and breastfeeding difficulties, the frequencies of which were compared with published general population frequencies. Pumping efficacy and milk flow parameters during a pumping session in PP mothers ( = 32) were compared with those that pump occasionally (reference group, = 60).
Examining Sociocultural Influences on Breastfeeding Attitudes Among Syrian and Hungarian Female Students.
Nutrients
January 2025
Department of Social Sciences, Faculty of Health Sciences, Semmelweis University, 1085 Budapest, Hungary.
Background: Breastfeeding in Syria is a common practice supported by social norms, family traditions, and cultural values. In Hungary, recent statistics show that exclusive breastfeeding is significantly lower than the recommendation of the World Health Organization. Understanding the perspectives of educated young ladies is crucial for discovering the difficulties of breastfeeding practices within Syrian-Hungarian societies.
View Article and Find Full Text PDFFecal Microbiome and Metabolomic Profiles of Mixed-Fed Infants Are More Similar to Formula-Fed than Breastfed Infants.
Microorganisms
January 2025
Department of Food Science & Human Nutrition, University of Illinois, Urbana, IL 61801, USA.
Many infants consume both human milk and infant formula (mixed-fed); however, few studies have investigated how mixed feeding affects the gut microbiome composition and metabolic profiles compared to exclusive breastfeeding or formula feeding. Herein, how delivery mode and early nutrition affect the microbiome and metabolome of 6-week-old infants in the STRONG Kids2 cohort was investigated. Fecal samples were collected from exclusively breastfed (BF; n = 25), formula-fed (FF; n = 25) or mixed-fed (MF; n = 25) participants.
View Article and Find Full Text PDFElevated Fecal Lipocalin-2 Levels During Early Life Are Associated with Maternal Inflammatory Bowel Disease Diagnosis.
Dig Dis Sci
January 2025
Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1425 Madison Ave, New York, NY, 10029, USA.
Background: Fecal lipocalin-2 (LCN2) is a biomarker of neutrophil activation, which is elevated in patients with inflammatory bowel disease (IBD); however, its dynamic changes during pregnancy and early life are largely unknown. We characterized LCN2 levels by maternal IBD diagnosis, offspring feeding behavior, and gut microbiota composition.
Methods: In the prospective MECONIUM (Exploring Mechanisms of Disease Transmission In Utero through the Microbiome) study, we analyzed 559 fecal samples from 91 pregnant women with IBD, 78 healthy controls, and their 147 offspring for LCN2 levels at each trimester of pregnancy and multiple time points during early life using linear mixed-effects model and multiple logistic regression analyses.
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