AI Article Synopsis
- Mycoplasma alligatoris and Mycoplasma crocodyli are closely related species, with M. alligatoris being highly virulent and M. crocodyli being less harmful.
- Research involved comparing their genomes to uncover the reasons behind M. alligatoris' high virulence in a group of generally less harmful microorganisms.
- Key differences were found in M. alligatoris, particularly in its genes related to sialidases and the N-acetylneuraminate scavenging and catabolism pathway.
Article Abstract
Mycoplasma alligatoris and Mycoplasma crocodyli are closely related siblings, one being highly virulent and the other relatively attenuated. We compared their genomes to better understand the mechanisms and origins of M. alligatoris' remarkable virulence amid a clade of harmless or much less virulent species. Although its chromosome was refractory to closure, M. alligatoris differed most notably by its complement of sialidases and other genes of the N-acetylneuraminate scavenging and catabolism pathway.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133112 | PMC |
| http://dx.doi.org/10.1128/JB.00309-11 | DOI Listing |
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