The analysis of the aerial parts of Bonannia graeca led to the isolation and characterization of polar geranylated flavonoids (6 and 7). The structure elucidation was performed by extensive spectroscopic methods (1D and 2D NMR) and comparison with literature data. All natural flavonoids isolated from B. graeca (1-7) and some synthetic derivatives (8-11) were tested for cytotoxic activity against four human tumor cell lines. Preliminary structure-activity relationship correlations are discussed.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151324 | PMC |
| http://dx.doi.org/10.1016/j.phytochem.2011.03.005 | DOI Listing |
Publication Analysis
Top Keywords
bonannia graeca
8
cytotoxic geranylflavonoids
4
geranylflavonoids bonannia
4
graeca analysis
4
analysis aerial
4
aerial parts
4
parts bonannia
4
graeca led
4
led isolation
4
isolation characterization
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!