Objective: The association of candy weight loss rate (CWLR) with whole saliva flow rates (WSFRs) was analyzed.
Study Design: The unstimulated whole saliva flow rate (UWSFR), stimulated whole saliva flow rate by the gum test (SWSFR-GT) and stimulated whole saliva flow rate by the Saxon test (SWSFR-ST) were measured in 300 healthy young adults. CWLR was measured by passively holding sugar candy between the tongue dorsum and hard palate. The degree of discomfort was evaluated by the visual analog scale.
Results: CWLR was significantly correlated with UWSFR, SWSFR-GT, and SWSFR-ST with Pearson's correlation coefficients of 0.1847 (P = .0013), 0.2097 (P = .0003), and 0.2332 (P < .0001), respectively; however, these were much smaller than those of 0.6858 (P < .0001) between UWSFR and SWSFR-GT, 0.5071 (P < .0001) between UWSFR and SWSFR-ST, and 0.5424 (P < .0001) between SWSFR-GT and SWSFR-ST. The degree of discomfort was significantly lower in the measurement of CWLR than in any WSFRs (P < .0001).
Conclusions: CWLR cannot be used as an independent alternative to WSFRs, although it can be measured with less discomfort.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.tripleo.2011.01.027 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
SHED-Derived Exosomes Ameliorate Sjögren's Syndrome-Induced Hyposalivation by Suppressing Th1 Cell Response via the miR-29a-3p/T-bet Axis.
ACS Appl Mater Interfaces
January 2025
Center Laboratory, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & Beijing Key Laboratory of Digital Stomatology & NHC Key Laboratory of Digital Stomatology & NMPA Key Laboratory for Dental Materials, No. 22, Zhongguancun South Avenue, Haidian District, Beijing 100081, P. R. China.
: Sjögren's syndrome (SS), an autoimmune disease, was characterized by sicca syndrome and systemic manifestations, presenting significant treatment challenges. Exosomes, naturally derived nanoparticles containing bioactive molecules, have garnered interest in regenerative medicine. The present study aimed to elucidate the immunoregulatory properties and mechanism of exosomes obtained from the stem cells derived from human exfoliated deciduous teeth (SHED-exos) in SS-induced sialadenitis.
View Article and Find Full Text PDFStudy on the repair function of radiation-induced salivary gland injury using human amniotic mesenchymal stem cells pre treated with hypoxia.
J Stomatol Oral Maxillofac Surg
January 2025
Department of Stomatology, the Fifth Affiliated Hospital of Zunyi Medical University, Zhuhai 519090, China. Electronic address:
Objective: To investigate the reparative effect of hypoxia pretreated hAMSCs on radiation-induced damage to salivary gland function in mice.
Methods: hAMSCs were separated from human amniotic tissues by mechanical and enzymatic digestion methods and a 15 Gy electron beam was used to locally irradiate the neck of mouse to create a salivary gland injury model. The mouse models were randomly divided into four groups: control group, IR+PBS group, IR+Nor group and IR+HP group.
Association between oral microbiome dysbiosis and Sjogren Syndrome. A systematic review of clinical studies.
Arch Oral Biol
December 2024
Department of Orofacial Pain and TMJ Disorders, Eastman Institute for Oral Health, University of Rochester, NY, USA. Electronic address:
Objectives: This systematic review investigates the association of oral microbiome dysbiosis with Sjogren Syndrome (SS).
Materials And Methods: Indexed databases (PubMed/Medline, EMBASE, OVID, Web of Science, and Scopus) were independently searched for relevant manuscripts published until August 2024. Clinical studies on oral microbial flora count and diversity in SS patients were included.
Differences in Salivary Cytokinome and Pathogen Load Between Rheumatoid Arthritis and Other Rheumatic Disease Patients.
Int J Mol Sci
December 2024
Department of Physiopathology, Faculty of Medicine, Medical University of Gdansk, 80-210 Gdansk, Poland.
Rheumatoid arthritis (RA), an autoimmune disease with complex pathogenesis, is characterized by an immune imbalance reflected, e.g., in the disturbed cytokines' profile.
View Article and Find Full Text PDFSalivary Flow Rate in Patients with Sjögren's Syndrome: Correlations with Salivary Gland Ultrasound Findings and Biomarkers of Disease Activity.
Int J Mol Sci
December 2024
Cardiology Department, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Sjögren's syndrome (SS) is a slowly progressive, chronic autoimmune inflammatory condition characterized by the affliction of the exocrine glands, with issues that derive from it markedly decreasing the quality of life of these patients. Salivary gland involvement can be identified through imaging methods. Among them, salivary gland ultrasonography (SGUS) is used as a diagnostic and prognostic tool in pSS.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!