This work addresses the synthesis, integration and characterization of a nanostructure-embedded thermoresponsive surface for flow regulation. In order to create a hierarchic structure which consists of microscale texture and nanoscale sub-texture, hybrid multilayers consisting of poly(allylamine hydrochloride) (PAH), poly(acrylic acid) (PAA) and colloidal silica nanoparticles (average diameter = 22 nm and 7 nm) were used. Based on the electrostatic interactions between the polyelectrolytes and nanoparticles, a layer-by-layer deposition technique in combination with photolithography was employed to obtain a localized, conformally-coated patch in a microchannel. Grafted with the thermoresponsive polymer, poly(N-isopropylacrylamide) (PNIPAAm), wettability of the surface could be tuned upon heating or cooling. The measurement of differential pressure at various stages of device verified the working conditions of the nanostructure-embedded surface for regulating a capillary flow in the microchannel.
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