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Rheumatoid arthritis: Are ACPA-positive and ACPA-negative RA the same disease? | LitMetric

Rheumatoid arthritis: Are ACPA-positive and ACPA-negative RA the same disease?

Nat Rev Rheumatol

Department of Rheumatology, Leiden University Medical Center, Albinusdreef 2, Leiden 2333ZA, The Netherlands.

Published: April 2011

Seemingly contrasting genetic backgrounds in anti-citrullinated-protein antibody (ACPA)-positive and ACPA-negative rheumatoid arthritis (RA) support the notion that these are in fact two distinct disease subsets, with different underlying pathogenesis, that might need tailored treatment strategies.

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Source
http://dx.doi.org/10.1038/nrrheum.2011.28DOI Listing

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