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| http://dx.doi.org/10.5688/ajpe7516 | DOI Listing |
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Specificity and sensitivity of ALT-associated markers in cancer cells.
FEBS Lett
January 2025
Dipartimento di Scienze, Università degli Studi "Roma Tre", Italy.
Some tumors employ a mechanism called alternative lengthening of telomeres (ALT) to counteract telomere shortening-induced replicative senescence. Several hallmarks are used to identify cell lines and tumors as ALT-positive. Here, we analyzed a panel of ALT-positive and -negative cancer cell lines to investigate the specificity and sensibility of ALT-associated markers.
View Article and Find Full Text PDFThe Effects of Systemic Tranexamic Acid Administration on Drainage Volume, Duration of Drain Placement, and Length of Hospital Stay in Skin- and Nipple-Sparing Mastectomies with Immediate Expander-Based Breast Reconstruction.
J Clin Med
October 2024
Faculty of Biomedical Sciences, Università della Svizzera Italiana, CH-6900 Lugano, Switzerland.
: Skin- (SSM) and nipple-sparing (NSM) mastectomies are frequently performed surgeries with a considerable risk for post-operative hematoma or seroma. Tranexamic acid (TXA) is a potent antifibrinolytic drug commonly used in many surgical fields but rather novel in plastic and, specifically, breast surgery. This study investigates the influence of TXA in patients undergoing SSM or NSM with expander-based reconstruction (EbR) on post-operative outcomes.
View Article and Find Full Text PDFEfficacy of Epidural Steroid in Controlling Pain After Unilateral Biportal Endoscopic Discectomy for Single-Level Lumbar Disc Herniation: A Randomized, Double-Blind, Placebo-Controlled Trial.
Int J Spine Surg
October 2024
Chulabhorn International College of Medicine, Thammasat University, Pathum Thani, Thailand
Background: The effects of epidural steroid (ES) administration following open or minimally invasive surgery lumbar discectomy have been extensively studied. However, no research has investigated the impact of steroids following the unilateral biportal technique endoscopic lumbar discectomy (UBE-D) for lumbar disc herniation. This study aims to evaluate the efficacy of ES administration in controlling postoperative pain and disability scores following UBE-D for single-level lumbar disc herniation.
View Article and Find Full Text PDFChallenges of a regional trauma center in treating combat and civilian casualties. The experience of Assuta Ashdod Hospital in the Iron Swords War.
Injury
January 2025
Samson Assuta Ashdod University Hospital, 7th Harefua Street, Ashdod, Israel; Faculty of Health Sciences, Ben Gurion University in the Negev, 4th Ben Gurion Boulevard, Beer Sheba, Israel.
Article Synopsis
- Assuta Ashdod Hospital was set up to help injured people during a violent event that started on October 7, 2023, and they focused on treating patients who couldn't be flown to other hospitals.
- They treated 397 seriously hurt patients, with most injuries happening in arms and legs, and many needed surgeries or blood transfusions.
- Despite challenges, the hospital had a good track record in helping many patients recover from their injuries.
A wide range of abiotic habitat factors and genetic diversity facilitate expansion of Trapa natans within its native range.
J Environ Manage
November 2024
Institute of Nature Conservation, Polish Academy of Sciences, al. Adama Mickiewicza 33, 31-120, Kraków, Poland. Electronic address:
Climate change and intense human activity are exacerbating changes in species' ranges. While the rapid spread of invasive alien species is well documented worldwide, the phenomenon of the spread of native species is poorly understood. To explain the problem of rapidly spreading species in the changing world, it is necessary to understand their ecology, genetic diversity and habitat limitation.
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