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| http://dx.doi.org/10.1093/ndt/gfr151 | DOI Listing |
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Background: Alzheimer's disease (AD) is a progressive neurodegenerative disease and the most prevalent type of senile dementia affecting more than 6 million Americans in 2023. Most of these AD cases are sporadic or late-onset AD with unclear etiology. Recent clinical trials on antibody drug clearing Ab plagues in brain show modest benefits of slowing down cognitive decline.
View Article and Find Full Text PDFMicrofragmented Adipose Tissue Has No Advantage Over Platelet-Rich Plasma and Bone Marrow Aspirate Injections for Symptomatic Knee Osteoarthritis: A Systematic Review and Meta-analysis.
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Orthopaedic Surgery, Weill Medical College of Cornell University, New York, New York, USA.
Background: Microfragmented adipose tissue has been proposed for intra-articular treatment of knee osteoarthritis. There are little data comparing the outcomes of treatment between microfragmented adipose tissue and other biological treatments.
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A novel approach for inferring effects on pregnancy loss.
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Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Identifying the determinants of pregnancy loss is a critical public health concern. However, pregnancy loss is often not noticed, and even when it is, it is inconsistently recorded. Thus, past studies have been limited to medically-identified losses or small, highly selected cohorts, which can lead to biased or non-generalizable results.
View Article and Find Full Text PDFOptimizing T cell inflamed signature through a combination biomarker approach for predicting immunotherapy response in NSCLC.
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Interventional Oncology, Johnson & Johnson Enterprise Innovation, Inc, 10th Floor 255 Main St, 02142, Cambridge, Boston, MA, USA.
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View Article and Find Full Text PDFPriority areas and implementation of ecological corridor through forest restoration to safeguard biodiversity.
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Departamento de Biodiversidade, Universidade Estadual Paulista, Rio Claro, SP, Brazil.
Ecological Corridors (ECs) are proposed as cost-effective solutions to improve ecological connectivity in fragmented landscapes. Planning the implementation of ECs must take into account landscape features as they affect the viability of the endeavor and the ECs associated costs. A novel set of geoprocessing tools were used to assess (i) economic viability; (ii) socioeconomic cost-effectiveness; and (iii) to determine priority targets for ECs establishment in a highly fragmented region of Atlantic Forest.
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