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Enhancing tuberculosis case notifications through mapping sales of medicine in the private sector: a quasi-experimental study in Punjab province, Pakistan.
BMC Health Serv Res
January 2025
Innovations & Grants, Stop TB Partnership, Global Health Campus - Chemin du Pommier 40, Le Grand-Saconnex, 1218, Geneva, Switzerland.
Introduction: In Pakistan, almost one-third of people who develop tuberculosis (TB) are missed by the National TB Program (NTP). A considerable number of people with TB receive treatment in the private sector but remain unnotified. This study documents the outcomes of an intervention to identify people with TB through private pharmacy engagement, building on mapping TB medicine sales in Punjab Province.
View Article and Find Full Text PDFExploring the perspectives of healthcare workers and Program managers on the use of Truenat as a new tool for TB and DR-TB diagnosis in Nigeria: A qualitative study.
PLoS One
January 2025
Department of Community Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Nigeria.
Background: World Health Organization in the year 2020 recommended the use of Truenat as a replacement for smear microscopy in Tuberculosis (TB) diagnosis and detection of rifampicin resistance. This study was designed to assess enablers and barriers to effective implementation of Truenat assays for TB diagnosis in Nigeria and determine the acceptability of use of Truenat among healthcare workers and TB Program managers in Nigeria.
Methods: A descriptive exploratory study design was used.
More nuance and transparency are needed when setting breakpoints for antimicrobial susceptibility testing of pretomanid.
Clin Microbiol Infect
December 2024
Department of Genetics, University of Cambridge, Cambridge, UK. Electronic address:
Acceptance and Completion Rates of 3-Month Isoniazid-Rifampicin (3HR) Tuberculosis Preventive Treatment (TPT) Among Contacts of Bacteriologically Confirmed TB Patients-Patients' and Healthcare Workers' Perspectives.
Trop Med Infect Dis
December 2024
Department of Community Medicine, Osun State University, Osogbo 230101, Nigeria.
Providing tuberculosis preventive treatment (TPT) to close contacts of persons with TB is a core strategy recommended by WHO for the prevention and control of TB. Nigeria rolled out the 3-month Isoniazid-Rifampicin (3HR) shorter regimen TPT as a pilot for use among eligible adult and child contacts. This study assesses acceptance and completion rates of 3HR TPT among contacts and determines the perspectives of healthcare workers (HCWs) and contacts on acceptance and completion of 3HR TPT in Nigeria.
View Article and Find Full Text PDFEvaluation of the Effectiveness of Global Tuberculosis Control Strategies at Different Stages and Analysis of Risk Factors: Findings From the Global Burden of Disease 2021.
Arch Bronconeumol
December 2024
Department of Public Health, Wuhan Fourth Hospital, Wuhan 430030, Hubei, China. Electronic address:
Background: The purpose of this study was to analyze the prevention and control effects of the three-phase global tuberculosis control strategy, and analyze the influencing factors.
Methods: We collected age-standardized incidence, prevalence, and mortality (ASIR, ASPR, and ASDR) data from the Global Burden of Disease Study (GBD 2021) database. Annual percentage change (AAPC) of ASIR, ASPR and ASDR were analyzed by Joinpoint regression.
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