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Superscan in First Posttherapeutic 177Lu-PSMA Scan.
Clin Nucl Med
December 2024
From the, Department of Nuclear Medicine, Faculty of Medicine, Selcuk University, Konya, Turkey.
This case highlights the effectiveness of 177Lu-PSMA therapy in a 70-year-old man with castration-resistant prostate cancer who has extensive skeletal metastases in posttherapeutic whole-body imaging. A 70-year-old man with extensive skeletal metastases underwent 4 cycles of 177 Lu-PSMA-617 therapy. A whole-body 177Lu-PSMA scan after the first cycle showed diffuse skeletal lesions, with minimal PSMA uptake in the kidneys and salivary glands.
View Article and Find Full Text PDFSuperscan Pattern on Bone Scintigraphy: A Comprehensive Review.
Diagnostics (Basel)
October 2024
Department of Nuclear Medicine, The Hospital for Sick Children, University of Toronto, Toronto, ON M4N 3M5, Canada.
Background/objectives: The superscan pattern is a characteristic finding on bone scintigraphy, associated with a variety of metabolic bone diseases, malignancies, and other conditions. This pattern is characterized by a diffuse and intense uptake of radiotracer throughout the entire skeleton. Despite being a relatively rare finding, the superscan pattern can have significant clinical implications.
View Article and Find Full Text PDFHigh-Grade Hepatic Spindle Cell Carcinoma as a Cause of Diffuse Right Hepatic Lobe Hypermetabolism Identified With 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (18F-FDG PET/CT) Imaging.
Cureus
September 2024
Nuclear Medicine and Positron Emission Tomography/Computed Tomography (PET/CT), King Hussein Cancer Center (KHCC), Amman, JOR.
Article Synopsis
- A 70-year-old man presented with severe symptoms including hiccups, belching, appetite loss, and significant weight loss over three months, prompting further investigation.
- F-FDG PET/CT imaging revealed a tumor in the right liver lobe exhibiting abnormal metabolic activity, indicating an aggressive form of cancer.
- A biopsy confirmed the diagnosis of high-grade spindle cell sarcoma, but the patient passed away shortly after, limiting treatment options.
Complimentary Role of [18F]FDG and [18F]NaF-PET/CT in Evaluating Synchronous Thyroid Carcinoma and Parathyroid Adenoma with Brown Tumors.
World J Nucl Med
September 2024
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital, Mumbai, Maharashtra, India.
We herein present a patient initially suspected of multiple lytic skeletal metastasis of unknown primary on anatomical imaging. Metabolic imaging by [18F]-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) detected focal [18F]FDG uptake in the right thyroid nodule, mild [18F]FDG uptake in soft tissue lesion in the left inferior parathyroid region, and multiple nonavid osteolytic skeletal lesions. Fine-needle aspiration cytology of the right thyroid nodule showed papillary thyroid carcinoma (PTC).
View Article and Find Full Text PDFCase report: F-FDG PET/CT skeletal superscan-like in an adult patient with acute lymphoblastic leukemia.
Front Oncol
July 2024
Department of Nuclear Medicine, The First College of Clinical Medical Science, China Three Gorges University, Yichang, China.
We herein describe a rare case of adult acute lymphoblastic leukemia with an florine-fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT) skeletal superscan-like appearance. The degree of bone marrow uptake was so intense that it far exceeded the level of physiological cerebral uptake and radiourinary activity. The distribution was remarkably similar to a superscan seen on skeletal scintigraphy.
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