The regulation of gene expression and the molecular basis of cancer.

Biomed Pharmacother

Laboratoire de recherche sur le cancer et les maladies du sang, Zone industrielle Grasbusch, Leudelange, Luxembourg.

Published: October 1990

Over the last few years, the advent of new genetic techniques allowed a detailed analysis of the structural and functional organization of the genome and the genes in a living cell. After the discovery of cellular oncogenes, genes which are implicated in cell growth control and differentiation, recent investigations provided evidence to a crucial role played by certain gene regulatory DNA elements and oncoproteins in the molecular mechanisms of carcinogenesis.

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http://dx.doi.org/10.1016/0753-3322(90)90023-3DOI Listing

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