We report the discovery of piperazine urea based compound 1, a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Compound 1 shows anti-obesity efficacy without potentiating erectile activity in the rodent models.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2011.02.090 | DOI Listing |
Publication Analysis
Top Keywords
discovery piperazine
8
piperazine urea
8
urea based
8
based compound
8
compound potent
8
potent selective
8
selective orally
8
orally bioavailable
8
bioavailable melanocortin
8
melanocortin subtype-4
8
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!