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Radiological and Pathological Analysis of Pembrolizumab-Associated Lung Lesions: Diagnostic Challenges and Management.
Am J Case Rep
January 2025
Department of Pulmonary and Critical Care Medicine, Faculty and Graduate School of Medicine, Mie University, Tsu, Mie, Japan.
BACKGROUND Pembrolizumab, a programmed cell-death protein-1 (PD-1)-targeting antibody, extends survival in cancer patients but may cause lung injury as a side effect. This immunotherapy enhances the immune system's ability to recognize and eliminate cancer cells. However, its immunomodulatory action can sometimes lead to immune-related adverse events, including lung injury.
View Article and Find Full Text PDFMetastatic Melanoma Causing Superior Vena Cava (SVC) Syndrome: A Case Report of a 65-Year-Old Male With a History of Multiple Myeloma and Melanoma.
Cureus
June 2024
Pulmonary and Critical Care Medicine, Jersey Shore University Medical Center, Neptune, USA.
Article Synopsis
- * The occurrence of SVC syndrome from metastatic melanoma is rare, especially compared to other types of cancer like lung cancer, making the data on this condition limited and inconsistent.
- * This case demonstrates the unusual nature of melanoma-related SVC syndrome and emphasizes the necessity for customized diagnostic and management strategies, contributing useful information to the medical field.
Black pigment on EBUS-TBNA sampling: A case of malignant melanoma.
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Thoracic Research Center, Imam Khomeini Hospital Complex Tehran University of Medical Sciences Tehran Iran.
The visualization of black pigment during EBUS-TBNA suggests a relapse of melanoma. This case highlights the value of EBUS-TBNA in diagnosing metastatic melanoma, particularly when the macroscopic appearance of the aspirate suggests the diagnosis.
View Article and Find Full Text PDFA Rare Pulmonary Metastasis of Uveal Melanoma Diagnosed Through Endobronchial Endosonography and Fine Needle Aspiration: A Case Report.
Arch Bronconeumol
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University Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain. Electronic address:
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Interventional Pulmonology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
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- Primary melanoma of the lung (PMML) is a rare type of lung tumor that is poorly understood and often confused with metastatic cancers.
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- The findings emphasize the need for more research to improve understanding and treatment options for PMML, given its complex nature and varying prognosis.
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