[Histological findings in an irradiated choroidal melanoma].

Background: Histological findings of choroidal melanomas after proton beam irradiation have been reported for complicated cases after enucleation. We present specimens of a tumor after transretinal probe excision.

Patient And Methods: One year after irradiation, the biopsy was examined histologically.

Results: The specimens showed pigmented, spindle-shaped cells staining positively for Melan-A and HMB-45. Ki-67 showed low proliferation. Caspase-3 staining was normal.

Conclusions: The melanoma still contained vital and even single proliferating cells, but regressed afterwards without additional therapy.