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Unusual Cutaneous Manifestations in a Patient with a History of Hepatitis B: A Case of Scleromyxedema and Literature Review.
Clin Cosmet Investig Dermatol
January 2025
Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, Guangdong, People's Republic of China.
Scleromyxedema (SM) is a rare primary cutaneous mucinosis characterized by systemic papules and scleroderma-like manifestations, often associated with monoclonal gammopathy. We present the case of a 37-year-old male with SM who developed yellowish plaques on the neck and back over three years. Histopathological examination revealed mucin deposition, fibroblast proliferation, and fibrosis, supporting the diagnosis.
View Article and Find Full Text PDFSuccessful Treatment of a Case of Scleromyxedema With Intravenous Immunoglobulin and Thalidomide and a Two-and-a-Half-Year Follow-Up.
Australas J Dermatol
January 2025
Department of Dermatology and Venereology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, India.
Unveiling the enigma: a case-based review of scleromyxedema.
Rheumatol Int
January 2025
Department of Rheumatology, Medical University of Lodz, Łódź, Poland.
Scleromyxedema is a rare chronic fibromucinous disorder characterized by a generalized papular and sclerodermoid eruption. Despite its clinical significance, no definitive therapeutic guidelines exist for scleromyxedema, making management challenging. Herein, we present a case of a 76-year-old female patient referred for evaluation of systemic sclerosis, presenting with distinctive cutaneous manifestations and neurological symptoms.
View Article and Find Full Text PDFParaproteinemia paradigm: Skin as a window to hematological malignancy.
QJM
December 2024
Assistant Professor, All India Institute of Medical Sciences, Delhi, 110029, India.
Scleromyxedema and Breast-Implant Associated Lymphoma: Investigating an Unusual Clinical Association.
Cureus
November 2024
Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Scleromyxedema, a rare skin condition, is characterized by a waxy-appearing papular eruption that tends to impact middle-aged adults. Scleromyxedema is often linked to monoclonal gammopathies. However, some patients do not have a coinciding monoclonal gammopathy and experience an atypical presentation of the disease.
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