Although drug-eluting stents have reduced the restenosis rate, some patients are not good candidates for prolonged double-antiplatelet therapy. Our goal was to learn the results of implanting cobalt-chromium stents in long lesions of large vessels.All consecutive patients with ≥1 lesion treated with a cobalt-chromium stent ≥28 mm in length and ≥3.5 mm in diameter during a 12-month period in 2 centers were monitored clinically and angiographically to determine the clinical status, restenosis rate, pattern of restenosis, and need for revascularization.The series comprised 78 patients with 81 lesions, mean age, 62.6 ± 15.2 yr; diabetes mellitus,19.2%; and primary or rescue intervention, 20.6%. Target vessels were the left anterior descending coronary artery, 12 (14.8%); left circumflex coronary artery, 12 (14.8%); and right coronary artery, 57 (70.4%). The mean lesion length was 35.18 ± 12.65 mm. The proximal reference diameter after percutaneous coronary intervention was 3.64 ± 0.54 mm; the distal, 3.2 ± 0.43 mm; and the mean, 3.42 ± 0.44 mm. The mean stent length was 38.05 ± 12.78 mm (range, 28-90 mm). The binary restenosis rate was 23% (15/64), with pattern IB in 2 cases, IC in 5, II in 7, and IV in 1. Revascularization was needed in 6 patients.In treating long lesions of large vessels, we found that cobalt-chromium stents achieved a moderate rate of target-vessel restenosis and a low rate of repeat revascularization. The pattern of restenosis was focal in almost half of the cases, and, in most remaining cases, restenosis affected short segments of the vessel.
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J Endovasc Ther
December 2024
Institute for Vascular Research, St. Franziskus Hospital, Münster, Germany.
Background: To compare the performance of a new-generation cobalt-chromium balloon-expandable bare metal stent with a stainless steel platform for the treatment of iliac occlusive disease.
Methods: Consecutive patients treated for symptomatic iliac occlusive disease between 2014 and 2021 with the cobalt-chromium Dynetic-35 or the stainless steel Dynamic platform were retrospectively evaluated. Outcome measures included technical success, device- or procedure-related death, clinically-driven target lesion revascularization (CD-TLR), primary patency, and major index limb amputation up to 12 months.
Acta Biomater
January 2025
Mechatronic, Electrical Energy and Dynamic Systems, Institute of Mechanics, Materials, and Civil Engineering, UCLouvain, 1348 Louvain-la-Neuve, Belgium; Pole of Morphology, Institute of Experimental and Clinical Research, UCLouvain, 1200 Woluwe-Saint-Lambert, Belgium; Department of Materials Engineering, KU Leuven, 3001 Leuven, Belgium; Prometheus, Division of Skeletal Tissue Engineering, KU Leuven, 3000 Leuven, Belgium. Electronic address:
Biodegradable intravascular stents offer a promising alternative to permanent stents for treating atherosclerosis-related artery narrowing by potentially avoiding long-term complications. Identifying materials that degrade harmlessly and uniformly at a suitable rate is crucial. This study evaluated an advanced zinc alloy (Zn-Ag-Cu-Mn-Zr) alongside pure iron and pure zinc, using a simplified stent model of metallic wires implanted in the rat aorta.
View Article and Find Full Text PDFComput Methods Biomech Biomed Engin
November 2024
Shanghai Institute for Minimally Invasive Therapy, University of Shanghai for Science and Technology, Shanghai, PR China.
This study investigates NiTi-CoCr hybrid carotid artery stents to enhance mechanical properties over NiTi-only designs. Different configurations (24NiTi, 20NiTi-4CoCr, 16NiTi-8CoCr, and 12NiTi-12CoCr) were evaluated through radial compression and bending simulations. The 12NiTi-12CoCr stent showed the highest radial support (39.
View Article and Find Full Text PDFMolecules
October 2024
Department of Chemical Engineering, McGill University, 3610 University St., Montreal, QC H3A 0C5, Canada.
An extracellular matrix protein, fibronectin (Fn), was covalently immobilized on 316L stainless steel, L605 cobalt chromium (CoCr), and nickel titanium (NiTi) surfaces through an 11-mercaptoundecanoic acid (MUA) self-assembled monolayer (SAM) pre-formed on these surfaces. Polarization modulation infrared reflection adsorption spectroscopy (PM-IRRAS) confirmed the presence of Fn on the surfaces. The Fn monolayer attached to the SAM was found to be stable under fluid shear stress.
View Article and Find Full Text PDFBackground: Flow diversion has revolutionized the management of wide-necked intracranial aneurysms (IAs). We aimed to assess the effectiveness and safety of the new generation 64-wire Surpass Evolve for the treatment of unruptured small/medium-sized IAs.
Methods And Results: This is a subanalysis from the SEASE (Safety and Effectiveness Assessment of the Surpass Evolve) registry, an observational cohort study including 15 academic institutions in North America and Europe between July 2020 and October 2022.
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