Dynamic and rapidly evolving nature of systems driven research imposes special requirements on the technology, approach, design and architecture of computational infrastructure including database and Web application. Several solutions have been proposed to meet the expectations and novel methods have been developed to address the persisting problems of data integration. It is important for researchers to understand different technologies and approaches. Having familiarized with the pros and cons of the existing technologies, researchers can exploit its capabilities to the maximum potential for integrating data. In this review we discuss the architecture, design and key technologies underlying some of the prominent databases and Web applications. We will mention their roles in integration of biological data and investigate some of the emerging design concepts and computational technologies that are likely to have a key role in the future of systems driven biomedical research.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059952 | PMC |
| http://dx.doi.org/10.3389/fphys.2010.00147 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Phase Switch Driven by the Hidden Half-Ice, Half-Fire State in a Ferrimagnet.
Phys Rev Lett
December 2024
Brookhaven National Laboratory, Condensed Matter Physics and Materials Science Division, Upton, New York 11973, USA.
The notion of "half fire, half ice" was recently introduced to describe an exotic macroscopic ground-state degeneracy emerging in a ferrimagnet under the critical magnetic field, in which the "hot" spins are fully disordered on the sublattice with smaller magnetic moments and the "cold" spins are fully ordered on the sublattice with larger magnetic moments. Here, we further point out that this state has a twin named "half ice, half fire" in which the hot and cold spins switch positions. The new state is an excited state-thus hidden in the ground-state phase diagram-and is robust with respect to the interactions that destroy the half-fire, half-ice state.
View Article and Find Full Text PDFSecond Law of Thermodynamics without Einstein Relation.
Phys Rev Lett
December 2024
Tel Aviv University, School of Mechanical Engineering and Center for Physics and Chemistry of Living Systems, 69978 Tel Aviv, Israel.
Materials that are constantly driven out of thermodynamic equilibrium, such as active and living systems, typically violate the Einstein relation. This may arise from active contributions to particle fluctuations which are unrelated to the dissipative resistance of the surrounding medium. We show that in these cases the widely used relation between informatic entropy production and heat dissipation does not hold.
View Article and Find Full Text PDFExotic Synchronization in Continuous Time Crystals Outside the Symmetric Subspace.
Phys Rev Lett
December 2024
Indian Institute of Technology, Department of Physics, -Bombay, Powai, Mumbai 400076, India.
Exploring continuous time crystals (CTCs) within the symmetric subspace of spin systems has been a subject of intensive research in recent times. Thus far, the stability of the time-crystal phase outside the symmetric subspace in such spin systems has gone largely unexplored. Here, we investigate the effect of including the asymmetric subspaces on the dynamics of CTCs in a driven dissipative spin model.
View Article and Find Full Text PDFAlgebraic Depletion Interactions in Two-Temperature Mixtures.
Phys Rev Lett
December 2024
Université de Mons, Laboratoire Interfaces & Fluides Complexes, 20 Place du Parc, B-7000 Mons, Belgium.
The phase separation that occurs in two-temperature mixtures, which are driven out of equilibrium at the local scale, has been thoroughly characterized, but much less is known about the depletion interactions that drive it. Using numerical simulations in dimension 2, we show that the depletion interactions extend beyond two particle diameters in dilute systems, as expected at equilibrium, and decay algebraically with an exponent -4. Solving for the N-particle distribution function in the stationary state, perturbatively in the interaction potential, we show that algebraic correlations with an exponent -2d arise from triplets of particles at different temperatures in spatial dimension d.
View Article and Find Full Text PDFTheory for Dissipative Time Crystals in Coupled Parametric Oscillators.
Phys Rev Lett
December 2024
University of Maryland, College Park, Joint Quantum Institute, Condensed Matter Theory Center and, Department of Physics, Maryland 20742-4111, USA.
Discrete time crystals are novel phases of matter that break the discrete time translational symmetry of a periodically driven system. In this Letter, we propose a classical system of weakly nonlinear parametrically driven coupled oscillators as a test bed to understand these phases. Such a system of parametric oscillators can be used to model period-doubling instabilities of Josephson junction arrays as well as semiconductor lasers.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!